North Carolina Family Practice PBRN

描述(由申请人提供)：北卡罗来纳州家庭实践实践研究网络(NCFP-PBRN)根据AHRQ RFA#HS-02-003建议进一步发展基础设施(第一类)和4个探索性/试点项目(第二类)。NCFP-PBRN由16个家庭实践场所组成，这些场所构成了国家实践环境的分层(农村/城市、地区)样本。它是由北卡罗来纳大学家庭医学系和瑟斯顿关节炎研究中心在疾病控制和预防中心提供的为期两年(2000-2002年)的赠款下建立的，并获得了补充机构资金，以促进少数族裔的招募。最初的资金用于研究补充和替代药物在关节炎中的使用；然而，从一开始，NCFP-PBRN的结构就旨在促进广泛的以初级保健为基础的研究，以具有代表性的实践群体和以实践为基础的成人患者队列为中心。NCFP-PBRN已经招募了大约4500名成人患者，他们是2001年从参与实践中招募的，目前正在维持这一队列。目前正在处理的论文使用了这一队列的数据，讨论了老年人中抑郁症的患病率，种族和与健康相关的生活质量之间的关系，以及关节炎患者使用补充和替代疗法。 拟议的项目将使NCFP-PBRN能够通过加强项目基础设施和沟通，并通过支持具有将研究成果转化为实践的资助项目的高潜力的试点研究，进一步发展其使命和在实现自我可持续性方面的进展。目标包括：1)制定研究协调的程序和人员，2)加强沟通联系，3)招聘4个以少数群体为重点的做法，4)开发社区健康指标数据库，5)进行4个试点研究。拟议的试点研究的主题包括II型糖尿病高危人群的体力活动、老龄化和慢性病中的性健康问题、初级保健中的临终规划以及生物恐怖主义的监测。拟议的试点研究中有三项寻求确定将研究证据应用于实践的有效战略；第四项研究将发展对少数群体的宝贵见解。

DESCRIPTION (provided by applicant): The North Carolina Family Practice Practice-Based Research Network (NCFP-PBRN) proposes further infrastructure development (Category I) and 4 exploratory/pilot projects (Category II), in response to AHRQ RFA #HS-02-003. The NCFP-PBRN consists of 16 family practice sites, which constitute a stratified (rural/urban, region) sample of the state's practice settings. It was founded by the Department of Family Medicine and the Thurston Arthritis Research Center at the University of North Carolina under a 2-year (2000-2002) grant from the Centers for Disease Control and Prevention, with supplemental institutional funding to enhance minority recruitment. Initial funding was awarded to study complementary and alternative medicine use in arthritis; however from its outset the NCFP-PBRN was structured with the intention of fostering a wide range of primary care-based studies, centered around a representative group of practices and a practice-based cohort of adult patients. The NCFP-PBRN has enrolled and is currently maintaining a cohort of approximately 4,500 adult patients who were recruited in 2001 from participating practices. Papers currently in process using data from this cohort address the prevalence of depression in older persons, the relationship between race and health-related quality of life, and use of complementary and alternative therapies by persons with arthritis. The proposed project will enable the NCFP-PBRN to further develop its mission and progress toward self sustainability by strengthening project infrastructure and communication, and by supporting pilot studies with high potential for leading to funded projects that translate research findings into practice. Aims include: 1) development of processes and personnel for research coordination, 2) enhancement of communication linkages, 3) recruitment of four minority-focused practices, 4) development of a community health indicators database, and 5) conducting four pilot studies. Topics of proposed pilot studies include physical activity in persons at high risk for type II diabetes, sexual health problems in aging and chronic illness, end-of-life planning in primary care, and surveillance for bioterrorism. Three of the proposed pilot studies seek to identify effective strategies to apply research evidence to practice; the fourth will develop valuable insights into minority populations.