Core--Morphology and imaging

形态学和成像核心是支持拟议研究的关键。形态学和成像核心的功能简要概述在四个方面：1）提供和处理标本原位杂交和免疫组织化学; 2）提供成像，数据，数据存储和检索的设施; 3）提供培训和支持形态学分析的各个方面;（4）选择蛋白质和基因标记物进行检测，以提供冠状动脉血管发育的综合分析。形态学和成像核心将集中我们的资源，为每个项目提供一致的、最先进的组织处理、成像和分析。核心还将作为一种机制，在项目之间传播结果，并开发、创建和维护发育和成熟冠状动脉血管中基因表达的综合数据库。鉴于每个项目对形态学分析的依赖，每个项目将使用形态学和成像核心中的大量可用资源。该核心的支持对于完成四个项目中每一个项目的既定目标至关重要。

The Morphology and Imaging Core is critical to the support of the studies proposed. The function of the Morphology and Imaging Core is briefly outlined in four areas: 1) To provide and process specimens for in situ hybridization and immunohistochemistry; 2) To provide a facility for imaging, data, data storage and retrieval; 3) To provide training and support for all aspects of morphological analysis; and 4) To assay selected protein and gene markers to provide a comprehensive analysis of coronary vessel development. The Morphology and Imaging Core will focus our resources to provide consistent, state-of-the-art tissue processing, imaging and analysis for each Project. The Core will also act as a mechanism to disseminate results between Projects and to develop, create and maintain a comprehensive data base for gene expressing in the developing and mature coronary vasculature. Given the reliance of each project on morphological analysis, each Project will use a significantg amount of the resources available in the Morphology and Imaging Core. The support of this Core is essential to completing the stated aims of each of the four individual projects.