Sampling Core

抽样核心是中心奖助金最重要的资源。它是通过 这一核心的运作是对符合指定年龄范围并定期献血的人类白细胞抗原血型献血者进行识别和标记，以便获得黄褐色外套。然后，将由伙伴外套生成的PBMC分发给可能需要它们的各种项目、技术组件或试点项目。该核心的第二个样本来源是将从有偿捐赠者那里获得的支气管肺泡灌洗(BAL)细胞。我们的合作者，威斯康星医学院的伊丽莎白·雅各布斯博士和兰道夫·利普奇克博士将获得BAL。核心将负责生成样本数据库，分发样本并将样本中未使用的部分存档 为以后可能的研究做准备。该中心将对样本进行一些常规分析，包括表面标志物分析和流感抗体效价的测量。核心是在杰克·戈尔斯基博士的指导下。

The Sampling Core serves as the most important resource for the Center Grant. It is through the operation of this Core that the HLA-typed blood donors who fall into the age range specified, and who donate blood on a regular basis, are identified and flagged so that the buffy coats can be obtained. The PBMC that are generated from the buddy coats are then distributed to the various projects, technical components or pilot projects that may require them. The second source of samples from this Core is bronchial alveolar lavage (BAL) cells that will be obtained from compensated donors. Our collaborators, Drs. Elizabeth Jacobs and Randolph Lipchik, at the Medical College of Wisconsin, will obtain the BAL. The Core will be responsible for a generation of a sample database, for sample distribution and archiving unused portions of the samples for possible later studies. The Core will perform some routine analyses on the samples that include surface marker analysis and measurement of influenza antibody titers. The Core is under the direction of Dr. Jack Gorski.