Computer Surgical Simulation for Craniofacial Surgery

描述：颅颌面（CMF）外科领域涉及颅骨和面部先天性和后天畸形的矫正。由于颅面骨骼的复杂性，这种类型的手术通常需要广泛的术前计划。在美国，每年都有大量的患者接受这些类型的手术重建。 这种类型的手术的传统手术计划方法涉及体格检查、X线平片（头影测量X线片）、石膏牙科模型、三维（3D）计算机断层扫描（CT）扫描，偶尔还包括基于CT的3D物理模型。不幸的是，这些方法往往不足以规划复杂的颅颌面畸形。 在过去的六年里，我们的手术计划实验室已经开发了一个计算机辅助手术模拟（卡斯）系统的原型。虽然我们的卡斯系统的准确性已经在体外进行了测试，但还没有在体内进行测试。因此，本I期申请的具体目的是确定使用研究者计算机辅助手术模拟系统的临床可行性。在第二阶段，研究人员计划开发一个用户友好的软件包，使外科医生能够计划复杂的颅颌面手术。该项目（第三阶段）的最终目标是将该产品推向市场。

DESCRIPTION: The field of craniomaxillofacial (CMF) surgery involves the correction of congenital and acquired deformities of the skull and face. Due to the complex nature of the craniofacial skeleton, this type of surgery usually requires extensive pre-surgical planning. In the United States each year, a significant number of patients undergo reconstruction for these types of operations. Traditional surgical planning methods for this type of the surgery involve a physical examination, plain radiographs (cephalometric radiographs), plaster Dental models, three-dimensional (3D) computed tomography (CT) scans, and occasionally CT-based 3D physical models. Unfortunately, these methods are often not adequate for planning complex craniomaxillofacial deformities. Over the last six years, our Surgical Planning Laboratory has developed a prototype for computer-assisted surgical simulation (CASS) system. Although the accuracy of our CASS system has been tested in vitro, it has not been tested in vivo. Therefore, the Specific Aim of this Phase I application will be to determine the clinical feasibility of using the investigators' computer-assisted surgical simulation system. In Phase II, the investigators plan to develop a user-friendly software package that will allow surgeons to plan complex craniomaxillofacial surgeries. The final goal of this project (Phase III) is to take this product to the market.