Computer Surgical Simulation for Craniofacial Surgery

颅面手术的计算机手术模拟

• 批准号: 6832917
• 负责人: JAIME GATENO
• 金额: $ 10万
• 依托单位: MEDICAL MODELING, LLC
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6832917
• 关键词: bioimaging /biomedical imaging; clinical research; computed axial tomography; computer program /software; computer simulation; computer system design /evaluation; congenital oral /facial /cranial defect; educational resource design /development; human subject; image guided surgery /therapy; patient oriented research; plastic surgery; three dimensional imaging /topography

DESCRIPTION: The field of craniomaxillofacial (CMF) surgery involves the correction of congenital and acquired deformities of the skull and face. Due to the complex nature of the craniofacial skeleton, this type of surgery usually requires extensive pre-surgical planning. In the United States each year, a significant number of patients undergo reconstruction for these types of operations. Traditional surgical planning methods for this type of the surgery involve a physical examination, plain radiographs (cephalometric radiographs), plaster Dental models, three-dimensional (3D) computed tomography (CT) scans, and occasionally CT-based 3D physical models. Unfortunately, these methods are often not adequate for planning complex craniomaxillofacial deformities. Over the last six years, our Surgical Planning Laboratory has developed a prototype for computer-assisted surgical simulation (CASS) system. Although the accuracy of our CASS system has been tested in vitro, it has not been tested in vivo. Therefore, the Specific Aim of this Phase I application will be to determine the clinical feasibility of using the investigators' computer-assisted surgical simulation system. In Phase II, the investigators plan to develop a user-friendly software package that will allow surgeons to plan complex craniomaxillofacial surgeries. The final goal of this project (Phase III) is to take this product to the market.

描述：颅颌面 (CMF) 手术领域涉及矫正颅骨和面部的先天性和后天性畸形。由于颅面骨骼的复杂性，此类手术通常需要广泛的术前计划。在美国，每年都有大量患者接受此类手术的重建。 此类手术的传统手术计划方法包括体检、X 线平片（头影测量 X 线照片）、石膏牙科模型、三维 (3D) 计算机断层扫描 (CT) 扫描，以及偶尔基于 CT 的 3D 物理模型。不幸的是，这些方法通常不足以规划复杂的颅颌面畸形。 在过去的六年里，我们的手术计划实验室开发了计算机辅助手术模拟 (CASS) 系统的原型。虽然我们的CASS系统的准确性已经在体外进行了测试，但尚未在体内进行测试。因此，第一阶段应用的具体目标是确定使用研究人员的计算机辅助手术模拟系统的临床可行性。在第二阶段，研究人员计划开发一个用户友好的软件包，使外科医生能够规划复杂的颅颌面手术。该项目（第三阶段）的最终目标是将该产品推向市场。