CORE--CLINICAL EPIDEMIOLOGY CORE

核心--临床流行病学核心

• 批准号: 6724370
• 负责人: I MARC MOSS
• 金额: $ 14.79万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-02-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6724370
• 关键词: adult respiratory distress syndrome; alcoholism /alcohol abuse; biomedical facility; clinical research; data management; human subject; intensive care; lung injury; substance abuse epidemiology

DESCRIPTION (provided by applicant): The Clinical Epidemiology Core (Core C) will support the clinical studies in this Center Grant application that are included in three of the projects and several of the pilot studies. Dr. Marc Moss will be the project leader of this core. He made the sentinel observation that chronic alcohol abuse increased the incidence and severity of ARDS in critically ill patients. He is also considered a national expect in clinical research methods in the critically ill as evidenced by his appointment to chair a symposium at the 2002 International American Thoracic Society meeting entitled, "Building the Critical Care Clinical Research Laboratory", and by his participation in the NIH-NHLBI Working Group on "Research Opportunities in the Clinical Epidemiology of Lung Injury and Critical Illness" in 2000. This Core will be primarily located at Grady Memorial Hospital but will routinely access the enormous quantity of critically ill patients in the 145 intensive care unit beds at the four Emory affiliated hospitals (Grady Memorial, Crawford Long, Emory University, and the Atlanta Veterans Administration). Dr. Moss has organized a cohesive team of investigators. These individuals draw upon the outstanding personnel at both the Emory School of Medicine and the Rollins School of Public Health at Emory University. These individuals will perform all of the necessary steps required to effectively identify and enroll patients into properly designed and accurately analyzed clinical studies. The core will also be responsible for ensuring that all institutional and federal policies regarding research involving human subjects are properly followed. This Alcohol and Critical Care Clinical Research Program has already been established and presently serves as an active working team. More importantly, this clinical core is a flexible system that can and will incorporate new members and encourage the growth, development, and implementation of new research protocols concerning novel hypotheses concerning the association between alcohol abuse and critical illness. i

描述（由申请人提供）：临床流行病学核心（核心C）将支持 该中心赠款应用中的临床研究包括在三个项目和一些试点研究中。马克·莫斯（Marc Moss）博士将成为该核心的项目负责人。他对哨兵的观察表明，慢性酒精滥用增加了重症患者的ARDS的发病率和严重程度。他还被认为是危重患病的临床研究方法的民族期望，他被任命为在2002年国际美国胸腔社会会议上主持研讨会的题为“建立“重症监护临床研究实验室”，以及他参与NIH-NHLBI工作组的参与，以“在临床上的临床疾病和临床疾病中的临床疾病”中的研究机会，但在2000年的临床疾病中，这是2000年。在四家埃默里附属医院（Grady Memorial，Crawford Long，Emory University，Emory University和Atlanta退伍军人管理局）的145张重症监护病房中，通常可以在145张重症监护病房中访问大量重症患者。莫斯博士组织了一个凝聚力的调查人员团队。这些人借鉴了埃默里医学院和埃默里大学罗林斯公共卫生学院的杰出人员。这些人将执行所有必要的步骤，以有效地识别并注册患者进行正确设计和准确分析的临床研究。核心还将负责确保适当遵循有关涉及人类受试者的研究的所有机构和联邦政策。这种酒精和重症监护 临床研究计划已经建立，目前是一个活跃的工作团队。更重要的是，该临床核心是一个灵活的系统，可以并且将融合新成员，并鼓励有关有关酗酒与重症疾病之间关联的新假设的新研究方案的增长，开发和实施。 我