SCORE Program at New Mexico State University, Las Cruces

新墨西哥州立大学拉斯克鲁塞斯分校 SCORE 项目

• 批准号: 6756082
• 负责人: GLENN D KUEHN
• 金额: $ 240.25万
• 依托单位: NEW MEXICO STATE UNIVERSITY LAS CRUCES
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6756082
• 关键词: health science research; health science research potential; minority institution research support

DESCRIPTION (provided by applicant): This is an application for a continuing SCORE Program at New Mexico State University (NMSU), Las Cruces. A goal of NMSU is to expand research at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has as its goals: (i) To transition, within the next four years, 74% of the investigators of regular SCORE subprojects in this application to competition for R01 funding from NIH. (ii) To enhance within the next four years, the publication records of all investigators of SCORE subprojects, who are in their second cycle of funding, to a minimum of 33% more research manuscripts per year in peer-reviewed, refereed journals. (iii) To significantly improve the capabilities of NMSU to conduct biomedically-relevant research through development of core research facilities. (iv) To improve the capacity of NMSU to self-evaluate, assess, and monitor the SCORE Program for the purpose of institutional self-study, program review, support of MORE Program missions, and internal improvement of research management. This application contains research proposals for nineteen research subprojects and three pilot subprojects. Disciplines represented among these proposals include Agronomy, Animal Science, Biochemistry, Biology, Chemistry, Molecular Biology, Microbiology and Psychology. The research topics of proposed projects include: mitosis and cytokinesis in animal cells, sensory organogenesis during inner ear development, genomic interactions of the growth hormone axis and leptin, pathogenicity in symbiotic vibrios, transcription factors in myogenic cells of electric fish, translational control of hepatitis C virus, adaptations of pigeons and rats to hypoxia, transmission of the pathogen, Cryptosporidium parvum, bacteriocide tolerance of Staphylococcus aureus, regulation of glutamine synthetase, programmed cell death studied by RNAi, electric and mechanical properties of bio-macromolecules, metal ion chelators for biomedical applications, high-valence iron complexes as models for non-heme iron proteins, chemical synthesis of radiopharmaceuticals, transcription regulation of secondary metabolism, organic synthesis of novel heterocyclic and aromatic compounds, transcriptional profiling of drought and salt tolerance in plants, selective binding of enantiomers by clays, and infant learning gauged by cortisol and behavioral synchrony. This SCORE Program will continue a 29-year MBRS Program which has advanced 351 minority students (approximately 81% of B.S.-graduated participants) to post-baccalaureate training, 72 earning Ph.D. degrees, since 1974.

描述（由申请人提供）：这是一个在拉斯克鲁塞斯的新墨西哥州州立大学（NMSU）继续SCORE计划的申请。NMSU的一个目标是扩大该机构的研究，让希望从事生物医学科学学科职业的少数民族学生参与。拟议的SCORE计划的目标是：（i）在未来四年内，将本申请中常规SCORE子项目的74%的研究者转变为竞争NIH的R01资金。(ii)为了在未来四年内提高SCORE子项目的所有研究人员的出版记录，他们正在第二个资助周期，每年在同行评审的期刊上至少增加33%的研究手稿。(iii)通过发展核心研究设施，显着提高NMSU进行生物医学相关研究的能力。(iv)提高NMSU自我评估，评估和监测SCORE计划的能力，以实现机构自学，计划审查，支持更多计划任务和内部改进研究管理的目的。 本申请包含十九个研究子项目和三个试点子项目的研究建议。这些建议中所代表的学科包括农学、动物科学、生物化学、生物学、化学、分子生物学、微生物学和心理学。建议项目的研究课题包括：动物细胞中的有丝分裂和胞质分裂，内耳发育过程中的感觉器官发生，生长激素轴和瘦素的基因组相互作用，共生弧菌中的致病性，电鱼肌细胞中的转录因子，丙型肝炎病毒的翻译控制，鸽子和大鼠对缺氧的适应，病原体的传播，隐孢子虫，金黄色葡萄球菌的杀菌剂耐受性，谷氨酰胺合成酶的调节，通过RNAi研究的程序性细胞死亡，生物大分子的电学和机械性质，用于生物医学应用的金属离子螯合剂，作为非血红素铁蛋白模型的高价铁络合物，放射性药物的化学合成，次级代谢的转录调节，新的杂环和芳香化合物的有机合成，植物耐旱和耐盐性的转录谱，粘土对映体的选择性结合，以及通过皮质醇和行为同步测量的婴儿学习。该SCORE计划将继续29年的MBRS计划，该计划已推进351名少数民族学生（约81%的B.S.毕业的参与者）到学士后培训，72人获得博士学位。自1974年以来，