Development of novel analytical approaches to make robust analyses more available

开发新颖的分析方法，使稳健的分析更加可用

• 批准号: 2338218
• 金额: --
• 依托单位: King's College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2338218
• 关键词: Development; novel; analytical; approaches; make

I have recently changed my primary research project to a collaborative project with the Department of Nutritional Sciences (Dr Balazs Bajka) developing analytical methods for detecting amino acids and fatty acids in biological samples in readily deployable formats.Proposed question - Usually, researchers take blood samples for analysis. This is costly and inconvenient and is not readily available to the whole population. To overcome these drawbacks, we ask and aim to investigate if amino acids and fatty acids can be detected and quantified from samples of dried blood spots, to enable larger cheaper nutritional studies.Methodology - this would start by learning and implementing standard protocols to develop a reference data set for comparison and developing novel analytical methods for the identification and detection and quantification of amino acids and fatty acids in dried blood spot samples. Another branch of the project is to develop methods to analyse products from in vitro digestion experiments which are done by nutritionists to assess nutrient bioavailiability.

我最近将我的主要研究项目改为与营养科学部(巴拉兹·巴伊卡博士)合作的一个项目，该项目开发分析方法，以便于部署的形式检测生物样本中的氨基酸和脂肪酸。提出的问题-通常，研究人员采集血液样本进行分析。这是昂贵和不便的，而且不是所有人都能轻易获得的。为了克服这些缺陷，我们要求并致力于研究是否可以从干血点样本中检测和量化氨基酸和脂肪酸，以实现更大规模、更便宜的营养研究。方法-这将从学习和实施标准方案开始，以开发用于比较的参考数据集，并开发新的分析方法来识别和检测和量化干血点样本中的氨基酸和脂肪酸。该项目的另一个分支是开发分析体外消化实验产品的方法，这些实验由营养学家完成，以评估养分的生物利用度。