REDUCING HIV RISK IN DRUG ABUSING YOUTH

描述：（申请人摘要） 这项拟议的4年研究的主要目的是比较 加强认知行为（E-CB）干预“标准护理” 在文化多样性、贫穷和弱势群体中减少艾滋病毒风险的条件 少数民族男性青少年罪犯（N=440）。 由于E-CB干预是 在法院授权的治疗背景下提供，它提供了一个独特的 有机会接触到一个极高风险群体， 不可能从事密集和专门的减少艾滋病毒风险的工作， 干预 虽然一些药物治疗计划的活动， E-CB的共同组成部分，这些活动不包括a） 在激励方面，加强了电子能力建设格式，鼓励参与者积极 协助制定自己的风险降低战略，以最适合 B）包括艾滋病毒风险特定的混合性别群体， 促进互动，重点是演练减少风险的战略; 以及c）强调认知行为策略，以科普 从住院状态到社区生活的转变。 目标2是评估 如果E-CB比SC更大程度地减少药物使用，AIM 3将评估 如果药物滥用（特别是快克可卡因）可以调解这种关系， 我们的干预措施和艾滋病毒风险结果之间的关系。 目标4是评估关键 变量介导我们的干预措施和艾滋病毒风险之间的关系 药物滥用的结果。 目的5是评估关键变量是否可能缓解 我们的干预措施与艾滋病风险和药物滥用之间的关系 结果。 探索性目的是评估E-CB是否产生更大的 对HIV检测行为和结果的积极治疗影响。 危险行为，吸毒，艾滋病和性病状况，艾滋病检测接受程度，毒品 和其他临床显著现象将在术前和术后6小时测量 干预后数月.. 多种方法（深入访谈，STD 和药物尿液分析）将用于证实和补充自我 报道 重复测量MANOVA和回归分析将用于 分析E-CB对HIV风险介导和结局变量的影响， 探讨中介、调节和结果之间的关系 变量

DESCRIPTION: (Applicant's Abstract) The primary aim of this proposed 4 year study compares the effects of an Enhanced Cognitive-Behavioral (E-CB) Intervention to a "Standard Care" Information Condition in reducing HIV risk among culturally diverse, poor minority male adolescent offenders (N=440). Since the E-CB intervention is offered in the context of court-mandated treatment, it provides a unique opportunity to reach an extremely high risk group that might otherwise be impossible to engage in an intense and specialized HIV risk reduction intervention. Although some of the drug treatment program activities share common components to the E-CB, these activities do not a) incorporate the motivationally, enhanced E-CB format of encouraging participants to actively assist in developing their own risk-reduction strategic to best suit their circumstances; b) include HIV risk specific mixed gender groups with facilitated interactions focused on rehearsing strategies to reduce risk; and c) emphasis on cognitive-behavioral strategies to cope with the transition from in-patient status to community living. AIM 2 is to evaluate if E-CB reduces drug use to a greater extent than SC. AIM 3 is to evaluate if drug abuse (particularly crack cocaine) may mediate the relationships between our interventions and HIV risk outcome. AIM 4 is to evaluate if key variables mediate the relationships between our interventions and HIV risk and drug abuse outcome. AIM 5 is to evaluate if key variables may moderate the relationships between our interventions and our HIV risk and drug abuse outcome. An EXPLORATORY AIM is to evaluate if E-CB produces greater positive therapeutic impact than SC on HIV testing behavior and results. Risk behavior, drug use, HIV and STD status, HIV testing acceptance, drug and other clinically significant phenomena will be measured at pre- and at 6 months post- intervention.. Multiple methods (in-depth interviewing, STD and drug urine analyses) will be used to corroborate and supplement self reports. Repeated measures MANOVA and regression analyses will be used to analyze the effects of E-CB on HIV risk mediating and outcome variables and to explore the relationships between mediating, moderating and outcome variables.