In vitro Investigation Assessing Erosive and Abrasive Toothwear Challenges on Natural Human Enamel
In vitro Investigation Assessing Erosive and Abrasive Toothwear Challenges on Natural Human Enamel
批准号:
2382941
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金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2019
资助国家:
英国
项目状态:
已结题
起止时间:
2019 至 --
中文摘要
鉴于牙齿磨损的历史文献一直围绕抛光牙釉质,现在在分析非均匀曲面方法的建议下,我们可以研究天然牙釉质的侵蚀和磨损的相互作用,同时探索可考虑其修改的再矿化剂和保护剂。首先-评估磨损参数及其对抛光牙釉质的侵蚀性牙齿磨损的影响-鉴于大多数研究之前都集中在抛光牙釉质上,我可以重现一些结果来提高我的实验能力吗?接下来比较磨损参数对牙齿侵蚀磨损对天然牙釉质的影响磨损和侵蚀和磨损开始使用合成salivaSamples将由切片-嵌入——抛光——样品确认平坦腐蚀性/研磨挑战——分析的分析首先将同意通过profilometerwe阶梯高度会议还将探索微观硬度和其他分析methodsthe方法将以上研究1 thesisStudy 2已经自然曲面现在进一步的研究探索使用硅胶将磨损模型带入可能的临床试验,并探索使用氟化物等药剂来确定预防磨损的用途
英文摘要
Given that the history of the literature for tooth wear has been around polished enamel and now with the advices in the methods in analysing non uniform curved surfaces can we investigate the interplay of erosion and abrasion on natural enamel along with this explore the remineralising and protective agents available with consideration to their modifications.To start with - Assess abrasion parameters and their impact on erosive tooth wear for polished enamel - given the majority of the research has previously focused on polished enamel can I reproduce some of the results to enhance my experimental ability Following this compare abrasion parameters on the impact of erosive tooth wear on natural enamelMethodology will see the exploration of both erosion, abrasion and erosion and abrasion to start with and use synthetic salivaSamples will be prepared by sectioning - embedding - polishing - sample to confirm flatness - erosive/abrasive challenges - analysis the analysis to start with will be assent of step height sessions via a profilometerwe will also look to explore micro hardness and other analytic methodsthe above methodology will be for study 1 in the thesisStudy 2 has moved to natural curved surfaces further studies are now both exploring the uses of silicone to take the wear model to a possible clinical trial as well as exploring the use of agents such as fluoride to determine use for wear prevention
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