Psychophysiology and Emotion Regulation in BPD

BPD 的心理生理学和情绪调节

• 批准号: 6837865
• 负责人: JANICE R KUO
• 金额: $ 3.16万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-16 至 2007-09-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6837865
• 关键词: behavioral /social science research tag; borderline personality disorder; clinical research; disease /disorder etiology; emotions; female; human subject; mental health epidemiology; mood disorders; neuropsychological tests; patient oriented research; predoctoral investigator; psychological stressor; psychopathology; psychophysiology; stimulus /response; women' s health

DESCRIPTION (provided by applicant): The proposed research tests Linehan's (1993) theory that Borderline Personality Disorder (BPD) is a disorder of pervasive emotion dysregulation. Linehan defines emotion dysregulation as high sensitivity and intense responding to emotional stimuli across various contexts. In this study, physiological measures of respiratory sinus arrhvthmia (RSA), skin conductance (SC), and self-report will be used to investigate if BPD individuals show indications of pervasive emotion dysregulation by exhibiting heightened emotional responses across multiple emotions and multiple contexts. Participants will engage m a personally-relevant audiotape task (context 1) in which they will hear a description of a time when they felt afraid, angry, sad, and no emotion, and a standardized task (context 2) where they view standardized fear, anger, sad, and neutral films. It is predicted that, at baseline, BPD and GAD patients will show indications of emotional sensitivity compared with normal controls. When exposed to the personally-relevant and standardized fear inductions, it is predicted that the BPD and GAD groups will exhibit increased emotional responding compared to normal controls. However, when exposed to the personally-relevant and standardized anger and sadness inductions, it is expected that the BPD group will exhibit higher emotional responding than both GAD and normal control groups, thus indicating evidence of pervasive emotion dysregulation This study is the first to study emotion dysregulation in BPD using both sympathetic and parasympathic (i.e., vagal tone) physiological measures in addition to self-report.

描述（由申请人提供）：拟议的研究测试Linehan（1993）的理论，即边缘型人格障碍（BPD）是一种普遍性情绪失调的疾病。Linehan将情绪调节障碍定义为对各种环境中的情绪刺激的高敏感性和强烈反应。在这项研究中，呼吸窦心律失常（RSA），皮肤电导（SC）和自我报告的生理措施将被用来调查，如果BPD个人表现出广泛的情绪失调的迹象，表现出高度的情绪反应，在多种情绪和多种情况下。参与者将参与一个与个人相关的录音带任务（上下文1），其中他们将听到对他们感到害怕，愤怒，悲伤和没有情绪的时间的描述，以及一个标准化任务（上下文2），他们观看标准化的恐惧，愤怒，悲伤和中性电影。据预测，在基线时，BPD和GAD患者将显示与正常对照相比的情绪敏感性的迹象。当暴露于个人相关和标准化的恐惧诱导时，预测BPD和GAD组与正常对照组相比将表现出增加的情绪反应。然而，当暴露于个人相关的和标准化的愤怒和悲伤诱导时，预计BPD组将表现出比GAD和正常对照组更高的情绪反应，从而表明普遍情绪失调的证据。迷走神经张力）生理测量。