The effects of maternal borderline personality disorder on toddler theory of mind development
母亲边缘性人格障碍对幼儿心理发展理论的影响
基本信息
- 批准号:10460417
- 负责人:
- 金额:$ 6.76万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-06-01 至 2023-05-31
- 项目状态:已结题
- 来源:
- 关键词:Active LearningAddressAdolescenceAdolescentAffectiveAgeAgreementAngerAttentionBehaviorBehavioralBiological ModelsBorderline Personality DisorderCaregiversChildChild BehaviorCodeDataDecelerationDevelopmentDiagnosisDisadvantagedEmotionalFamilyFosteringFrequenciesFunctional disorderGoldHeart RateHostilityImpairmentIndividualInterventionKnowledgeLeadLearningLifeMaternal BehaviorMeasurementMeasuresMediatingMental disordersMindModelingMother-Child RelationsMothersNational Institute of Mental HealthNursery SchoolsOnset of illnessParentsPatternPerceptionPhasePhysiologicalPhysiologyPlayPreschool ChildPreventionPrevention ResearchProcessPsychophysiologyResearchResearch Domain CriteriaRiskRisk BehaviorsRisk FactorsRoleSamplingSeriesSocial ProcessesStrategic PlanningSymptomsTestingTimeToddlerTrainingWithdrawalagedanalytical methodapproach behaviorbasecatalystcostdynamic systemearly childhoodexperiencefallsfollow-uphigh riskimprovedindexingmaladaptive behaviormental statenoveloffspringpreventresponsesevere mental illnessskillssocial engagementsocial influencesocial learningsuicidal behaviorsymptomatologytheories
项目摘要
PROJECT SUMMARY/ABSTRACT
Theory of mind (ToM) is the ability to perceive and understand mental states in others a nd represents one
operationalization of the RDoC construct of Perception and Understanding of Others. ToM is an early emerging
mechanism in the development of borderline personality disorder (BPD); individuals with BPD tend to
misattribute mental states to others, spurring a cycle of anger dysregulation, interpersonal dysfunction, and
suicidal behavior. Aligned with the 2020 NIMH strategic plan, to identify malleable targets for prevention of BPD,
it is necessary to study the unfolding of this critical mechanism prior to the onset of symptomatology. The current
proposal aims to do so in a high-risk mother-child sample in which mothers have BPD and offspring are 36-48
months old, a critical time for ToM development. Further, this study will elucidate the specific behaviors that
mothers with BPD engage in that influence the development of ToM during the preschool period as well as child
behaviors involved in this process. ToM undergoes rapid development during the preschool age and is highly
susceptible to environmental influence, particularly interactions with caregivers. This proposal details a
comprehensive training plan that will enable me to address these questions while building on previous
experiences in important ways. First, expanding on my experience studying ToM and related processes in
adolescence, I will focus on the developmental trajectory of this construct during the preschool age. Second, I
will obtain training in measurement and interpretation of heart rate and RSA as physiological markers of
preschooler social engagement with mothers. Third, building on my knowledge of global behavioral coding of
mother-adolescent interactions, I will master the use of micro-analytic coding to obtain continuous time-series
data of mother and child behavior within interactions. Further, I will learn novel analytic methods for this unique
data based on dynamic systems modeling. The specific aims of this study are to 1) Determine whether two forms
of maladaptive maternal behaviors--hostility and inaccurate mental state attribution--are observed more often
among mothers with BPD compared to those with no psychiatric disorder; 2) Evaluate how preschooler social
engagement with mothers (i.e., approach and withdrawal behaviors as well as heart rate and RSA) is influenced
by these maternal behaviors; and 3) Test the effect of identified maternal behaviors on the trajectory of ToM
development over the course of one year in preschoolers. The central hypothesis of this proposal is that maternal
BPD is associated with maladaptive behaviors directed toward their children. These behaviors lead to a pattern
of dysfunctional social engagement by preschoolers (decreased approach and increased withdrawal behavior
toward mother during as well as heart rate deceleration and RSA withdrawal), which further inhibits their ToM
development during this critical phase. By identifying risk factors associated with ToM, families at risk can be
targeted for specific interventions focused on improving the quality of mother-child interactions, which may have
the effect of preventing BPD onset in offspring.
项目概要/摘要
心智理论 (ToM) 是一种感知和理解他人心理状态的能力,代表一种
对他人的感知和理解的 RDoC 结构的可操作性。 ToM 是一种较早出现的
边缘性人格障碍(BPD)发展的机制;患有 BPD 的人倾向于
将精神状态错误地归因于他人,从而引发愤怒失调、人际功能障碍和
自杀行为。与 2020 年 NIMH 战略计划保持一致,确定预防 BPD 的可塑目标,
有必要在症状出现之前研究这一关键机制的展开。目前的
该提案旨在在高风险母子样本中进行此研究,其中母亲患有 BPD,而子女年龄为 36-48 岁
几个月前,是 ToM 开发的关键时期。此外,本研究将阐明特定行为
患有 BPD 的母亲参与的活动会影响学前时期 ToM 的发展以及儿童
这个过程中涉及到的行为。 ToM在学龄前发展迅速,具有很高的应用价值。
容易受到环境影响,特别是与护理人员的互动。该提案详细说明了
全面的培训计划将使我能够在以前的基础上解决这些问题
重要方面的经验。首先,扩展我研究 ToM 和相关流程的经验
青春期时,我将重点关注学龄前这一建构的发展轨迹。第二,我
将获得测量和解释心率和 RSA 作为生理标志的培训
学龄前儿童与母亲的社交活动。第三,基于我对全球行为编码的了解
母亲与青少年的互动,我将掌握使用微观分析编码来获取连续的时间序列
母亲和孩子在互动中的行为数据。此外,我将学习这种独特的新颖的分析方法
基于动态系统建模的数据。本研究的具体目的是 1) 确定两种形式是否
更频繁地观察到适应不良的母亲行为——敌意和不准确的精神状态归因
患有 BPD 的母亲与没有精神疾病的母亲相比; 2) 评估学龄前儿童的社交能力
与母亲的互动(即接近和退缩行为以及心率和 RSA)受到影响
通过这些母亲的行为; 3) 测试已识别的母亲行为对 ToM 轨迹的影响
学龄前儿童一年内的发展。该提案的中心假设是,母亲
边缘性人格障碍与针对孩子的适应不良行为有关。这些行为导致了一种模式
学龄前儿童社交参与功能失调(接触减少和退缩行为增加
以及心率减慢和 RSA 撤回期间对母亲的影响),这进一步抑制了他们的 ToM
在这个关键阶段的发展。通过识别与 ToM 相关的风险因素,处于风险中的家庭可以
针对以提高母子互动质量为重点的具体干预措施,这可能会
预防后代 BPD 发病的效果。
项目成果
期刊论文数量(7)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Maternal invalidation and child RSA reactivity to frustration interact to predict teacher-reported aggression among at-risk preschoolers.
- DOI:10.1017/s0033291722003713
- 发表时间:2023-10
- 期刊:
- 影响因子:6.9
- 作者:Byrd AL;Frigoletto OA;Vine V;Vanwoerden S;Jennings JR;Zalewski M;Stepp SD
- 通讯作者:Stepp SD
Are We Thinking about the Same Disorder? A Trifactor Model Approach to Understand Parents' and Their Adolescents' Reports of Borderline Personality Pathology.
我们正在考虑同样的疾病吗?
- DOI:10.1080/00223891.2022.2039165
- 发表时间:2023
- 期刊:
- 影响因子:3.4
- 作者:Vanwoerden,Salome;McLaren,Veronica;Stepp,StephanieD;Sharp,Carla
- 通讯作者:Sharp,Carla
The role of youths' cardiac autonomic balance and parental responses to youth emotion in vulnerability to borderline personality disorder development.
青少年心脏自主平衡和父母对青少年情绪的反应在易患边缘性人格障碍发展中的作用。
- DOI:10.1017/s095457942300024x
- 发表时间:2023
- 期刊:
- 影响因子:3.3
- 作者:Vanwoerden,Salome;Vine,Vera;Byrd,AmyL;Jennings,JRichard;Stepp,StephanieD
- 通讯作者:Stepp,StephanieD
Sampling methods in personality pathology research: Some data and recommendations.
人格病理学研究中的抽样方法:一些数据和建议。
- DOI:10.1037/per0000593
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Vanwoerden,Salome;Chandler,Jesse;Cano,Kiana;Mehta,Paras;Pilkonis,PaulA;Sharp,Carla
- 通讯作者:Sharp,Carla
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, alternative model conceptualization of borderline personality disorder: A review of the evidence.
- DOI:10.1037/per0000563
- 发表时间:2022-07
- 期刊:
- 影响因子:2.8
- 作者:Vanwoerden, Salome;Stepp, Stephanie D
- 通讯作者:Stepp, Stephanie D
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Salome Vanwoerden其他文献
Salome Vanwoerden的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Salome Vanwoerden', 18)}}的其他基金
Dysfunctional behavior with friends during middle childhood as a precursor to borderline personality pathology
童年中期与朋友的功能失调行为是边缘人格病理学的先兆
- 批准号:
10806402 - 财政年份:2023
- 资助金额:
$ 6.76万 - 项目类别:
The effects of maternal borderline personality disorder on toddler theory of mind development
母亲边缘性人格障碍对幼儿心理发展理论的影响
- 批准号:
10231836 - 财政年份:2021
- 资助金额:
$ 6.76万 - 项目类别:
The Development and Validation of an Observational Coding System for Real-Time Parent-Adolescent Mentalizing
实时父母青少年心智化观察编码系统的开发和验证
- 批准号:
9762625 - 财政年份:2017
- 资助金额:
$ 6.76万 - 项目类别:
The Development and Validation of an Observational Coding System for Real-Time Parent-Adolescent Mentalizing
实时父母青少年心智化观察编码系统的开发和验证
- 批准号:
9397259 - 财政年份:2017
- 资助金额:
$ 6.76万 - 项目类别:
相似海外基金
Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
- 批准号:
MR/S03398X/2 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Fellowship
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
- 批准号:
EP/Y001486/1 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Research Grant
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
- 批准号:
2338423 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Continuing Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
- 批准号:
MR/X03657X/1 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
- 批准号:
2348066 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
- 批准号:
AH/Z505481/1 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10107647 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
EU-Funded
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
- 批准号:
2341402 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Standard Grant
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10106221 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
- 批准号:
AH/Z505341/1 - 财政年份:2024
- 资助金额:
$ 6.76万 - 项目类别:
Research Grant














{{item.name}}会员




