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The effects of maternal borderline personality disorder on toddler theory of mind development

母亲边缘性人格障碍对幼儿心理发展理论的影响

基本信息

批准号：
10460417
负责人：
Salome Vanwoerden
金额：
$ 6.76万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-06-01 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10460417
关键词：
Active Learning Address Adolescence Adolescent Affective Age Agreement Anger Attention Behavior Behavioral Biological Models Borderline Personality Disorder Caregivers Child Child Behavior Code Data Deceleration Development Diagnosis Disadvantaged Emotional Family Fostering Frequencies Functional disorder Gold Heart Rate Hostility Impairment Individual Intervention Knowledge Lead Learning Life Maternal Behavior Measurement Measures Mediating Mental disorders Mind Modeling Mother-Child Relations Mothers National Institute of Mental Health Nursery Schools Onset of illness Parents Pattern Perception Phase Physiological Physiology Play Preschool Child Prevention Prevention Research Process Psychophysiology Research Research Domain Criteria Risk Risk Behaviors Risk Factors Role Sampling Series Social Processes Strategic Planning Symptoms Testing Time Toddler Training Withdrawal aged analytical method approach behavior base catalyst cost dynamic system early childhood experience falls follow-up high risk improved indexing maladaptive behavior mental state novel offspring prevent response severe mental illness skills social engagement social influence social learning suicidal behavior symptomatology theories

项目摘要

PROJECT SUMMARY/ABSTRACT Theory of mind (ToM) is the ability to perceive and understand mental states in others a nd represents one operationalization of the RDoC construct of Perception and Understanding of Others. ToM is an early emerging mechanism in the development of borderline personality disorder (BPD); individuals with BPD tend to misattribute mental states to others, spurring a cycle of anger dysregulation, interpersonal dysfunction, and suicidal behavior. Aligned with the 2020 NIMH strategic plan, to identify malleable targets for prevention of BPD, it is necessary to study the unfolding of this critical mechanism prior to the onset of symptomatology. The current proposal aims to do so in a high-risk mother-child sample in which mothers have BPD and offspring are 36-48 months old, a critical time for ToM development. Further, this study will elucidate the specific behaviors that mothers with BPD engage in that influence the development of ToM during the preschool period as well as child behaviors involved in this process. ToM undergoes rapid development during the preschool age and is highly susceptible to environmental influence, particularly interactions with caregivers. This proposal details a comprehensive training plan that will enable me to address these questions while building on previous experiences in important ways. First, expanding on my experience studying ToM and related processes in adolescence, I will focus on the developmental trajectory of this construct during the preschool age. Second, I will obtain training in measurement and interpretation of heart rate and RSA as physiological markers of preschooler social engagement with mothers. Third, building on my knowledge of global behavioral coding of mother-adolescent interactions, I will master the use of micro-analytic coding to obtain continuous time-series data of mother and child behavior within interactions. Further, I will learn novel analytic methods for this unique data based on dynamic systems modeling. The specific aims of this study are to 1) Determine whether two forms of maladaptive maternal behaviors--hostility and inaccurate mental state attribution--are observed more often among mothers with BPD compared to those with no psychiatric disorder; 2) Evaluate how preschooler social engagement with mothers (i.e., approach and withdrawal behaviors as well as heart rate and RSA) is influenced by these maternal behaviors; and 3) Test the effect of identified maternal behaviors on the trajectory of ToM development over the course of one year in preschoolers. The central hypothesis of this proposal is that maternal BPD is associated with maladaptive behaviors directed toward their children. These behaviors lead to a pattern of dysfunctional social engagement by preschoolers (decreased approach and increased withdrawal behavior toward mother during as well as heart rate deceleration and RSA withdrawal), which further inhibits their ToM development during this critical phase. By identifying risk factors associated with ToM, families at risk can be targeted for specific interventions focused on improving the quality of mother-child interactions, which may have the effect of preventing BPD onset in offspring.

项目概要/摘要心智理论 (ToM) 是一种感知和理解他人心理状态的能力，代表一种对他人的感知和理解的 RDoC 结构的可操作性。 ToM 是一种较早出现的边缘性人格障碍（BPD）发展的机制；患有 BPD 的人倾向于将精神状态错误地归因于他人，从而引发愤怒失调、人际功能障碍和自杀行为。与 2020 年 NIMH 战略计划保持一致，确定预防 BPD 的可塑目标，有必要在症状出现之前研究这一关键机制的展开。目前的该提案旨在在高风险母子样本中进行此研究，其中母亲患有 BPD，而子女年龄为 36-48 岁几个月前，是 ToM 开发的关键时期。此外，本研究将阐明特定行为患有 BPD 的母亲参与的活动会影响学前时期 ToM 的发展以及儿童这个过程中涉及到的行为。 ToM在学龄前发展迅速，具有很高的应用价值。容易受到环境影响，特别是与护理人员的互动。该提案详细说明了全面的培训计划将使我能够在以前的基础上解决这些问题重要方面的经验。首先，扩展我研究 ToM 和相关流程的经验青春期时，我将重点关注学龄前这一建构的发展轨迹。第二，我将获得测量和解释心率和 RSA 作为生理标志的培训学龄前儿童与母亲的社交活动。第三，基于我对全球行为编码的了解母亲与青少年的互动，我将掌握使用微观分析编码来获取连续的时间序列母亲和孩子在互动中的行为数据。此外，我将学习这种独特的新颖的分析方法基于动态系统建模的数据。本研究的具体目的是 1) 确定两种形式是否更频繁地观察到适应不良的母亲行为——敌意和不准确的精神状态归因患有 BPD 的母亲与没有精神疾病的母亲相比； 2) 评估学龄前儿童的社交能力与母亲的互动（即接近和退缩行为以及心率和 RSA）受到影响通过这些母亲的行为； 3) 测试已识别的母亲行为对 ToM 轨迹的影响学龄前儿童一年内的发展。该提案的中心假设是，母亲边缘性人格障碍与针对孩子的适应不良行为有关。这些行为导致了一种模式学龄前儿童社交参与功能失调（接触减少和退缩行为增加以及心率减慢和 RSA 撤回期间对母亲的影响），这进一步抑制了他们的 ToM 在这个关键阶段的发展。通过识别与 ToM 相关的风险因素，处于风险中的家庭可以针对以提高母子互动质量为重点的具体干预措施，这可能会预防后代 BPD 发病的效果。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Maternal invalidation and child RSA reactivity to frustration interact to predict teacher-reported aggression among at-risk preschoolers.

DOI：
10.1017/s0033291722003713
发表时间：
2023-10
期刊：
Psychological medicine
影响因子：
6.9
作者：
Byrd AL;Frigoletto OA;Vine V;Vanwoerden S;Jennings JR;Zalewski M;Stepp SD
通讯作者：
Stepp SD

Are We Thinking about the Same Disorder? A Trifactor Model Approach to Understand Parents' and Their Adolescents' Reports of Borderline Personality Pathology.

我们正在考虑同样的疾病吗？

DOI：
10.1080/00223891.2022.2039165
发表时间：
2023
期刊：
Journal of personality assessment
影响因子：
3.4
作者：
Vanwoerden,Salome;McLaren,Veronica;Stepp,StephanieD;Sharp,Carla
通讯作者：
Sharp,Carla

The role of youths' cardiac autonomic balance and parental responses to youth emotion in vulnerability to borderline personality disorder development.

青少年心脏自主平衡和父母对青少年情绪的反应在易患边缘性人格障碍发展中的作用。

DOI：
10.1017/s095457942300024x
发表时间：
2023
期刊：
Development and psychopathology
影响因子：
3.3
作者：
Vanwoerden,Salome;Vine,Vera;Byrd,AmyL;Jennings,JRichard;Stepp,StephanieD
通讯作者：
Stepp,StephanieD

Sampling methods in personality pathology research: Some data and recommendations.

人格病理学研究中的抽样方法：一些数据和建议。

DOI：
10.1037/per0000593
发表时间：
2023
期刊：
Personality disorders
影响因子：
0
作者：
Vanwoerden,Salome;Chandler,Jesse;Cano,Kiana;Mehta,Paras;Pilkonis,PaulA;Sharp,Carla
通讯作者：
Sharp,Carla

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, alternative model conceptualization of borderline personality disorder: A review of the evidence.