Object Representation in the Lateral Occipital Cortex

枕叶外侧皮层中的物体表征

• 批准号: 6835870
• 负责人: DAMIAN A STANLEY
• 金额: $ 2.67万
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6835870
• 关键词: behavioral /social science research tag; brain imaging /visualization /scanning; brain mapping; clinical research; cues; functional magnetic resonance imaging; human subject; neural information processing; occipital lobe /cortex; predoctoral investigator; visual perception; visual stimulus

DESCRIPTION (provided by applicant): The Lateral Occipital Complex (LOC) is a large region of the human occipital and temporal lobes that has been consistently implicated in a variety of object recognition processes. It has been suggested that the LOC consists of more than one functional region, but few studies have focused on this issue. In particular, it is not known whether the LOC contains regions that process multi-modal object information. We hypothesize that the LOC consists of (at least) two functional units; the posterior (occipital) parts are involved in purely visual processing and the anterior (temporal) parts are involved in multi-modal integration of object knowledge. We will use functional Magnetic Resonance Imaging (fMRI) to examine systematically the relationship between specific functional sub-processes of object recognition and loci of activation in the LOC. Specifically, we propose: 1) To study whether there is a relation between the -visual complexity- of a stimulus and the extent to which it activates anterior versus posterior portions of LOC. 2) To study whether increased -object familiarity- (as a result of increased exposure or knowledge of object context) will result in an expansion of activation from posterior regions of LO into anterior regions.

描述（由申请人提供）：枕外侧复合体（LOC）是人类枕叶和颞叶的一个大区域，一直与各种物体识别过程有关。有人认为 LOC 由多个功能区组成，但很少有研究关注这一问题。特别是，尚不清楚 LOC 是否包含处理多模式对象信息的区域。我们假设 LOC 由（至少）两个功能单元组成；后部（枕叶）部分涉及纯粹的视觉处理，前部（颞叶）部分涉及对象知识的多模态整合。我们将使用功能磁共振成像 (fMRI) 来系统地检查目标识别的特定功能子过程与 LOC 中激活位点之间的关系。具体来说，我们建议：1）研究刺激的“视觉复杂性”与其激活 LOC 前部和后部的程度之间是否存在关系。 2) 研究增加的“物体熟悉度”（由于暴露或了解物体背景的增加）是否会导致激活从LO的后部区域扩展到前部区域。