Information Technologies to Improve Patient Adherence

描述（由申请人提供）：本申请要求五年 支持Raymond L。Ownby，医学博士，博士，从事研究和培训， 应用认知老化和人为因素的研究，适用于病人- 导向研究。通过Sara J. Czaja博士的指导，Ownby博士不会 我只会发展专业知识，将这些领域的技能应用于关键问题 （老年记忆障碍患者的药物依从性），但也会 建立一个老年心理健康循证实践中心。的 在支持期间完成的研究将使用两个 信息技术干预，以提高患者的依从性， 药物治疗。基于坚持医疗的模式 由Park和Jones（1997年）开发，信息干预将针对关键 在药物治疗过程中。试点研究表明， 该模型对于本研究的患者群体（老年人）的使用是有效的 有记忆问题的患者，他们要么有发展或有发展风险， 阿尔茨海默病）。在过去两年的支持中，Ownby博士将 根据研究结果制定研究建议， 开展信息技术大规模多中心临床试验 其他地区研究中心和其他患者依从性干预措施 人口。预计该申请将通过以下方式寻求资金： RO 1机制。本集团将继续致力于为客户提供优质的服务。 Ownby包括与Czaja博士定期会面，就拟议的研究开展工作 研究，教学课程，讲习班，并在人类领域的研讨会 因素，信息技术，统计，研究设计，循证 实践和负责任的研究行为。通过定期会议 和研究监督他的导师和定期会议与共同导师， Ownby博士将能够将他的专业经验整合为临床 精神病学家和神经心理学家，受过人为因素的教学培训， 应用认知老化来创造新的策略，以改善患者 坚持，开发这些策略的大规模临床试验，并 应用循证实践的原则，建立一个证据中心- 在迈阿密大学实习。这个中心的使命是 透过有系统的方法，传播老人精神健康的研究成果。 综述、荟萃分析和治疗指南， 传统的出版途径和万维网。该中心将促进 信息技术应用于心理健康的新研究 老年人的问题，并提供领导和培训， 临床实践的信息。专业发展计划将 从而使Ownby博士能够发展创造信息技术的专业知识， 应用在医疗保健与老年人，为他提供关键 设计和实施大规模临床试验的工具，并使 他利用研究结果来指导临床实践， 老年医学因此，拟议的支持期将使Ownby博士能够 发展成为能够以病人为中心的临床研究人员 研究研究，并给他更多的工具，在应用认知老化， 人的因素研究，特别是新兴信息的应用。

DESCRIPTION (provided by applicant): This application requests five years of support for Raymond L. Ownby, MD, PhD, to pursue research and training in applied cognitive aging and human factors research as applied to patient- oriented research. Through mentoring by Sara J. Czaja, PhD, Dr. Ownby will not only develop expertise in applying skills in these areas to a critical problem (medication adherence in elderly patients with memory deficits) but will also create a center for evidence-based practice in geriatric mental health. The research study to be completed during the period of support will use two information technology interventions to improve patients' adherence with medication regimens. Base on a model of adherence to medical treatment developed by Park and Jones (1997), information interventions will target key points in the medication adherence process. Pilot research has suggested that this model is valid for use with the patient population of this study (elderly patients with memory problems who either have or are at risk for developing Alzheimer's disease). During the last two years of support, Dr. Ownby will develop a research proposal drawing on results of the research study to develop a large-scale multicenter clinical trial of information technology interventions for adherence in other geographical sites and with other patient populations. It is anticipated that this application will seek funding through the RO1 mechanism. The professional development program to be followed by Dr. Ownby comprises regular meetings with Dr. Czaja, work on the proposed research study, didactic coursework, workshops, and seminars in the areas of human factors, information technologies, statistics, research design, evidence-based practice, and the responsible conduct of research. Through regular meetings and research supervised by his mentor and regular meetings with co-mentors, Dr. Ownby will be able to integrate his professional experience as a clinical psychiatrist and neuropsychologist with didactic training in human factors and applied cognitive aging to create novel strategies to improve patient adherence, to develop a large-scale clinical trial of these strategies, and to apply principles of evidence-based practice to develop a Center for Evidence- Based Practice at the University of Miami. This center's mission will be to disseminate research findings in geriatric mental health through systematic reviews, meta-analyses~ and treatment guidelines made available through traditional publication routes and the World Wide Web. The Center will foster new research in applications of information technologies to the mental health problems of the elderly and provide leadership and training in applying information to clinical practice. The professional development program will thus allow Dr. Ownby to develop expertise in creating information technology applications for use in healthcare with the elderly, provide him with key tools in designing and carrying out large-scale Clinical trials, and enable him to use results of research studies to guide clinical practice in geriatrics. The period of proposed support will thus allow Dr. Ownby to develop as a clinical researcher capable of carrying out patient-oriented research studies and give him additional tools in applied cognitive aging and human factors research, especially applications of emerging information.