Photo-Responsive Luminescent Lanthanide Complexes

光响应发光稀土配合物

• 批准号: 2404180
• 金额: --
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2404180
• 关键词: Photo; Responsive; Luminescent; Lanthanide; Complexes

Photo-switches are chemical compounds that can switch between two stable forms when light is shone onto the compound. A common example is a class of compounds called azobenzenes. They work similarly to a light switch on the wall, when the stimulus is applied this induces a change. In the case of a switch in your home the stimulus is your hand and the change is whether the light is switched on or off. Whereas with the photo-switch, the light is the stimulus and the output is, in the case of azobenzene molecules, a change in length of the compound. Photo-switches have functions in sensors, electronic devices, and in medical and biological applications. For example drug release could be stimulated by light or the mechanisms involved in responsive biological systems, such as ion channels, can be further understood. Using photo-switches within a more complicated system can lead to control over the forms of photo-switch present and thus their interactions with other compounds in the system.Lanthanides are a group of elements which have unique properties. One property is long- lived luminescent (the ability to emit light), in comparison to the luminescence of biological species. Research has found that this luminescence can be controlled by the presence of other compounds (chromophores) which can either change the intensity of the luminescence or turn off the luminescence completely. This switchable property means that emission can be turned on or off depending on the nature and state of the interacting chromophore. This makes them exciting compounds for bio-imaging. Their optical properties also make them attractive compounds for optic-electronic devices, such as screens and displays.The aim of this project is to engineer a system in which the azobenzene photo-switch influences the luminescence of the lanthanide. For this to work, energy transfer between the two species must occur. Energy transfer can either happen through space and is dependent on how close the two species are relative to each other (Forster Resonance Energy transfer) or directly though a bond attaching the two species together (Dexter Energy transfer). Understanding and determining the mechanism of energy transfer aids in the engineering of a switchable luminescent lanthanide complex. In addition, the type of azobenzene and lanthanide chosen need to be considered. Recently azobenzenes have been discovered that switch length when visible light is shone onto them, these are promising candidates as visible light is much less destructive to surrounding enviroments than UV-light. The lanthanide chosen must have good luminescent properties and in order to work well with the azobenzene it must be able to absorb/emit light in a similar range to the light that induces switching in the azobenzene.Combining azobenzene photo-switches and lanthanide complexes is a new area in chemistry. Both separately are well researched, however there has only been a few examples when the two have been combined in a single system. Through synthesising a new photo-responsive lanthanide complex, in which the luminescence can be influenced by the length of the azobenzene leads to the possibility of many new and exciting discoveries. This project falls within the ESPRC physical sciences research area.

光开关是一种化合物，当光线照射到化合物上时，它可以在两种稳定形式之间切换。一个常见的例子是一类称为偶氮苯的化合物。它们的工作原理类似于墙上的电灯开关，当施加刺激时，会引起变化。如果你家里有一个开关，那么刺激就是你的手，而变化就是灯是开还是关。而对于光开关，光是刺激物，在偶氮苯分子的情况下，输出是化合物长度的变化。光开关在传感器、电子设备以及医学和生物学应用中具有功能。例如，可以通过光刺激药物释放，或者可以进一步理解响应生物系统中涉及的机制，例如离子通道。在更复杂的体系中使用光开关可以控制光开关的存在形式，从而控制它们与体系中其他化合物的相互作用。镧系元素是一组具有独特性质的元素。与生物物种的发光相比，一种特性是长寿命发光（发光的能力）。研究发现，这种发光可以通过其他化合物（发色团）的存在来控制，这些化合物可以改变发光强度或完全关闭发光。这种可切换的性质意味着发射可以根据相互作用的发色团的性质和状态而打开或关闭。这使它们成为生物成像的令人兴奋的化合物。它们的光学性质也使它们成为光电器件的有吸引力的化合物，如屏幕和显示器。本项目的目的是设计一个系统，其中偶氮苯光开关影响镧系元素的发光。要做到这一点，两个物种之间必须发生能量转移。能量转移可以通过空间发生，并且取决于两种物质彼此之间的距离（福斯特共振能量转移），或者直接通过将两种物质连接在一起的键（德克斯特能量转移）。理解和确定能量转移的机制有助于可切换发光镧系元素络合物的工程设计。此外，需要考虑所选择的偶氮苯和镧系元素的类型。最近发现偶氮苯在可见光照射下的开关长度，这些是有希望的候选者，因为可见光对周围环境的破坏比紫外光小得多。选择的镧系元素必须具有良好的发光特性，并且为了与偶氮苯良好地工作，它必须能够吸收/发射与诱导偶氮苯中的开关的光类似的范围内的光。这两种方法都有很好的研究，但只有少数几个例子将两者结合在一个系统中。通过合成一种新的光响应性镧系配合物，其中发光可以受到偶氮苯长度的影响，导致许多新的和令人兴奋的发现的可能性。该项目属于ESPRC物理科学研究领域的福尔斯。