Depression and Physical Functioning in Older Adults

老年人的抑郁和身体机能

• 批准号: 6704742
• 负责人: CELIA F HYBELS
• 金额: $ 10.44万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6704742
• 关键词: aging; behavioral /social science research tag; clinical research; depression; functional ability; health behavior; human subject; interview; longitudinal human study; mental health epidemiology; psychological aspect of aging; psychotropic drugs

DESCRIPTION (provided by applicant): The proposed research is in response to PA-00-019, Mentored Research Scientist Development Award (K01). The candidate is an Assistant Research Professor in the Department of Psychiatry at Duke University. Duke University has a well-established research program in the areas of psychiatric epidemiology and multi-dimensional aspects of aging. The candidate has a strong background in survey research and holds graduate degrees in epidemiology. Her immediate career goals are to further increase her substantive expertise in aging, geriatric psychiatry, and psychiatric epidemiology with a continued focus on depression in late life, develop her quantitative skills through the use of advanced statistical models for the analysis of longitudinal data, and become more proficient in the publication process. Long-term career goals include the conduct of investigator-initiated research within the environment of an academic research center. The proposed plan will include time for independent study, attendance at seminars, conducting data analysis and learning new statistical techniques, manuscript preparation, and developing independent R01 applications near the completion of the award. The proposed research project will be undertaken to explore the interrelationship of depression and physical functioning in a community sample of older adults over time. Specifically, the aims will be 1) to develop an explanatory model of this interrelationship; 2) to compare the trajectories of depression and physical functioning over a ten-year follow-up period; and 3) to identify demographic and social factors as well as indicators of physical health status that affect these trajectories overtime. Data from the Duke Established Populations of Epidemiologic Studies of the Elderly (EPESE) will be used to develop the model and address the dynamics of the depression and functioning relationship.

描述（由申请人提供）：拟议的研究是对PA-00-019，指导研究科学家发展奖（K01）的回应。候选人是杜克大学精神病学助理研究教授。杜克大学在精神流行病学和衰老的多维方面有一个完善的研究项目。该候选人在调查研究方面有很强的背景，并拥有流行病学研究生学位。她近期的职业目标是进一步提高她在老龄化、老年精神病学和精神病学方面的专业知识，继续关注晚年抑郁症，通过使用先进的统计模型分析纵向数据来发展她的定量技能，并在出版过程中更加熟练。长期职业目标包括在学术研究中心的环境中进行研究者发起的研究。拟议的计划将包括独立学习，参加研讨会，进行数据分析和