Depression and Physical Functioning in Older Adults

老年人的抑郁和身体机能

• 批准号: 6832195
• 负责人: CELIA F HYBELS
• 金额: $ 10.65万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6832195
• 关键词: aging; behavioral /social science research tag; clinical research; depression; functional ability; health behavior; human subject; interview; longitudinal human study; mental health epidemiology; psychological aspect of aging; psychotropic drugs

DESCRIPTION (provided by applicant): The proposed research is in response to PA-00-019, Mentored Research Scientist Development Award (K01). The candidate is an Assistant Research Professor in the Department of Psychiatry at Duke University. Duke University has a well-established research program in the areas of psychiatric epidemiology and multi-dimensional aspects of aging. The candidate has a strong background in survey research and holds graduate degrees in epidemiology. Her immediate career goals are to further increase her substantive expertise in aging, geriatric psychiatry, and psychiatric epidemiology with a continued focus on depression in late life, develop her quantitative skills through the use of advanced statistical models for the analysis of longitudinal data, and become more proficient in the publication process. Long-term career goals include the conduct of investigator-initiated research within the environment of an academic research center. The proposed plan will include time for independent study, attendance at seminars, conducting data analysis and learning new statistical techniques, manuscript preparation, and developing independent R01 applications near the completion of the award. The proposed research project will be undertaken to explore the interrelationship of depression and physical functioning in a community sample of older adults over time. Specifically, the aims will be 1) to develop an explanatory model of this interrelationship; 2) to compare the trajectories of depression and physical functioning over a ten-year follow-up period; and 3) to identify demographic and social factors as well as indicators of physical health status that affect these trajectories overtime. Data from the Duke Established Populations of Epidemiologic Studies of the Elderly (EPESE) will be used to develop the model and address the dynamics of the depression and functioning relationship.

描述（由申请人提供）：拟定的研究是对PA-00-019，指导研究科学家发展奖（K 01）的回应。候选人是杜克大学精神病学系的助理研究教授。 杜克大学在精神病流行病学和老龄化的多维度方面有一个完善的研究计划。候选人在调查研究方面有很强的背景，并拥有流行病学研究生学位。她的近期职业目标是进一步提高她在老龄化，老年精神病学和精神病学流行病学方面的实质性专业知识，并继续关注晚年的抑郁症，通过使用先进的统计模型分析纵向数据来发展她的定量技能，并在出版过程中变得更加熟练。长期的职业目标包括在学术研究中心的环境中进行研究员发起的研究。拟议的计划将包括独立学习的时间，参加研讨会，进行数据分析， 学习新的统计技术，手稿准备，并在接近完成奖项时开发独立的R 01应用程序。拟议的研究项目将进行探讨抑郁症和身体功能的相互关系，随着时间的推移，在社区样本的老年人。 具体而言，目标是：1）开发这种相互关系的解释模型; 2）比较十年随访期间抑郁和身体功能的轨迹; 3）确定人口统计学和社会因素以及影响这些轨迹的身体健康状况指标。来自杜克大学老年人流行病学研究（EPESE）的数据将用于开发模型，并解决抑郁症和功能关系的动态。