Motivating Obese Adolescents to Reduce Risk for Diabetes

激励肥胖青少年降低糖尿病风险

• 批准号: 6750723
• 负责人: CARA B EBBELING
• 金额: $ 12.82万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-15 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6750723
• 关键词: adolescence (12-20); behavioral /social science research tag; body composition; clinical research; clinical trials; counseling; diabetes education; diet therapy; disease /disorder prevention /control; exercise; female; human subject; human therapy evaluation; insulin sensitivity /resistance; motivation; noninsulin dependent diabetes mellitus; obesity; parent offspring interaction; patient oriented research; prediabetic state; weight control

DESCRIPTION (provided by applicant):Modification of diet and physical activity behaviors is the cornerstone of treatment for preventing type 2 diabetes in obese adolescents. However, teenagers often are ambivalent about changing behaviors. This ambivalence may underlie poor long-term outcomes with conventional treatment programs. While adolescents want autonomy and may resist advice, they need parental support to achieve success with treatment. Many questions concerning behavioral and metabolic effects of strategies for treating obese adolescents remain unanswered and represent promising areas for future research. From a long-term perspective, Dr. Ebbeling is committed to a career focusing on how motivational and behavioral processes interact with metabolic effects of diet and physical activity to influence maintenance of weight loss and reduced risk for type 2 diabetes. A research career award will provide the opportunity for her to 1) expand her knowledge of type 2 diabetes, behavior change theory, and adolescent health; 2) integrate new knowledge with her expertise in nutrition, physical activity, and obesity in designing innovative motivational interventions; and 3) take a leadership role in conducting a clinical trial. The proposed research project will be a critical vehicle for career development and has important implications for reducing morbidities associated with obesity and type 2 diabetes. The aim of the project is to evaluate a directive, patient-centered counseling style for 1) assisting obese girls (13 to 16 years) in modifying diet and physical activity behaviors and 2) equipping their mothers to provide needed support. Daughter-mother dyads (N=40) will be randomized to Motivational Behavior Change Counseling (MBCC) or Standard of Care Counseling (SCC) for 6 months, with treatments controlled for contact time. According to study hypotheses, changes in primary (diet quality, physical activity) and secondary (body mass index, insulin resistance) outcomes will be more favorable with MBCC compared to SCC. Familial factors that influence behaviors are among several mediating variables that will be explored. In an environment that fosters development of junior faculty, interactions with Drs. Ludwig, Peterson, Sorensen, and Wypij will ensure successful completion of this project and promote Dr. Ebbeling's progress towards independence.

描述（由申请人提供）：饮食和身体活动行为的改变是预防肥胖青少年 2 型糖尿病的治疗基石。然而，青少年对于改变行为常常感到矛盾。这种矛盾心理可能是传统治疗方案长期效果不佳的原因。虽然青少年想要自主权并且可能会拒绝建议，但他们需要父母的支持才能取得成功的治疗。关于肥胖青少年治疗策略的行为和代谢影响的许多问题仍未得到解答，并且代表了未来研究的有希望的领域。从长远来看，Ebbeling 博士致力于研究动机和行为过程如何与饮食和身体活动的代谢影响相互作用，从而影响体重减轻的维持并降低 2 型糖尿病的风险。研究职业奖将为她提供机会：1) 扩展她对 2 型糖尿病、行为改变理论和青少年健康的知识； 2) 将新知识与她在营养、体育活动和肥胖方面的专业知识相结合，设计创新的激励干预措施； 3) 在开展临床试验中发挥领导作用。拟议的研究项目将成为职业发展的关键工具，对于减少与肥胖和 2 型糖尿病相关的发病率具有重要意义。该项目的目的是评估一种以患者为中心的指导性咨询方式：1) 协助肥胖女孩（13 至 16 岁）改变饮食和身体活动行为，2) 帮助她们的母亲提供所需的支持。母女二人组 (N = 40) 将被随机分配接受动机行为改变咨询 (MBCC) 或标准护理咨询 (SCC)，为期 6 个月，并控制接触时间。根据研究假设，与 SCC 相比，MBCC 的主要（饮食质量、体力活动）和次要（体重指数、胰岛素抵抗）结果的变化将更加有利。影响行为的家庭因素是我们将探讨的几个中介变量之一。在促进初级教师发展的环境中，与博士的互动。 Ludwig、Peterson、Sorensen 和 Wypij 将确保该项目的成功完成，并推动 Ebbeling 博士走向独立。