CORE--Cell Culture Facilities Core

CORE--细胞培养设施核心

• 批准号: 6750897
• 负责人: Thomas A Kocarek
• 金额: $ 22.55万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6750897
• 关键词: Kupffer' s cell; biomedical facility; cell differentiation; environmental toxicology; genetic regulation; tissue /cell culture; tissue /cell preparation

Description (provided by applicant): The mission of the Cell Culture Facility Core (CCFC) is to support the goals of the EHS Center Research Cores by providing their investigators with the cell culture systems, methodologies, equipment and technical assistance that will enable them to address important questions in the environmental health sciences, with human emphasis. The CCFC mission is accomplished by providing 1) physical space, equipment and supplies for performing cell culture work, 2) cell culture services that meet the needs of the Center Research Core members and 3) technical assistance, education and training. By providing Center investigators with these services and capabilities, the CCFC represents an enabling resource that facilitates the design and implementation of new collaborative, multi-disciplinary research projects. The CCFC was one of the four original facility cores that were established with the EHS Center. The CCFC currently occupies laboratories measuring more than 1,000 square feet that are outfitted with all equipment necessary to perform routine cell culture work, as well as specialized cell culture activities. Eleven services are offered through the CCFC, the primary goals of which are to 1) help investigators place cells into culture, 2) help investigators perform their own cell culture experiments, 3) improve the consistency and quality of cell cultures and 4) enhance the abilities of investigators to study biological processes in mechanistic detail. During the past funding cycle, the CCFC has supported the research activities of 22 Center members, and has enhanced the productivity of these investigators. In addition, the CCFC has catalyzed the emergence of new research ideas via continuous collaborations among Center investigators.

描述（由申请人提供）：细胞培养设施核心（CCFC）的使命是通过为研究人员提供细胞培养系统、方法、设备和技术援助，支持EHS中心研究核心的目标，使他们能够解决环境健康科学中的重要问题，重点是人类。CCFC的使命是通过提供1）物理空间，设备和用品进行细胞培养工作，2）细胞培养服务，以满足中心研究核心成员的需求和3）技术援助，教育和培训。通过为中心研究人员提供这些服务和能力，CCFC代表了一个有利的资源，促进了新的合作，多学科研究项目的设计和实施。CCFC是与EHS中心建立的四个原始设施核心之一。CCFC目前拥有超过1，000平方英尺的实验室，配备了进行常规细胞培养工作以及专业细胞培养活动所需的所有设备。CCFC提供11项服务，其主要目标是1）帮助研究人员将细胞放入培养物中，2）帮助研究人员进行自己的细胞培养实验，3）提高细胞培养物的一致性和质量，4）提高研究人员研究生物过程的能力。在过去的资助周期中，CCFC支持了22个中心成员的研究活动，并提高了这些研究人员的生产力。此外，CCFC通过中心研究人员之间的持续合作，促进了新研究思路的出现。