Core--NMR and Crystallography

核心——核磁共振和晶体学

• 批准号: 6725956
• 负责人: Michael P Stone
• 金额: $ 14.45万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6725956
• 关键词: biomedical equipment resource; biomedical facility; electron crystallography; environmental toxicology; nuclear magnetic resonance spectroscopy; protein structure; structural biology

Description (provided by applicant): The NMR and Crystallography Facility Core provides users from the Center in Molecular Toxicology with state-of-the-art NMR spectroscopy and protein crystallography instrumentation. The instrumentation is used not only for routine analysis, but also with the expertise of core personnel, to allow development of experimental methods that further the research objectives of the center. The facility is organized by the Vanderbilt University Structural Biology Program, directed by Professor Chazin, and operates jointly as core facility of the Center in Molecular Toxicology. Dr. Jaison Jacob is in charge of the daily operation of the NMR laboratory and a search is currently open for a Ph.D. staff scientist to oversee operations in the crystallography facilities. Physically, the NMR instrumentation is housed at two sites in the Stevenson Science Center and the crystallography instrumentation is housed in the Robinson Research Building in the Medical Center. The NMR and Crystallography Core play as prominent role in the center. This core operates both as a service core facility for analytical needs in NMR spectrometry and for complex NMR and Crystallography studies in Structural Biology.

描述（由申请人提供）：NMR和晶体学设施核心为分子毒理学中心的用户提供最先进的NMR光谱学和蛋白质晶体学仪器。该仪器不仅用于常规分析，而且还与核心人员的专业知识相结合，以开发实验方法，进一步实现中心的研究目标。该设施由范德比尔特大学结构生物学项目组织，由Chazin教授指导，并作为分子毒理学中心的核心设施共同运作。Jaison Jacob博士负责NMR实验室的日常运作，目前正在寻找博士学位。科学家监督晶体学设施的运作。物理上，核磁共振仪器位于史蒂文森科学中心的两个地点，晶体学仪器位于医学中心的罗宾逊研究大楼。核磁共振和晶体学核心在中心发挥着突出的作用。该核心作为服务核心设施运行，用于NMR光谱分析和结构生物学中复杂的NMR和晶体学研究。