Effectiveness of School Based Supervised Asthma Therapy

学校监督哮喘治疗的有效性

• 批准号: 6703257
• 负责人: Lynn B Gerald
• 金额: $ 72.42万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6703257
• 关键词: asthma; behavioral /social science research tag; clinical research; clinical trials; corticosteroids; elementary school; human morbidity; human subject; human therapy evaluation; longitudinal human study; medically underserved population; patient oriented research; pediatrics; quality of life; respiratory disease /disorder therapy; respiratory disorder chemotherapy; respiratory therapy; self care; therapy compliance; therapy design /development; urban poverty area

DESCRIPTION (provided by applicant): Pediatric asthma is a substantial cause of morbidity in children. Much of this morbidity is preventable as it can be directly attributable to lack of adherence to medical regimens. The consequence of non-adherence for most patients is exacerbations. Inhaled corticosteroids offer considerable protection against asthma exacerbations. However, very few children take their medications as recommended by the National Asthma Education and Prevention Program Guidelines. Therefore, adherence to medication is essential for ultimate reductions in morbidity. Asthma morbidity is higher in inner-city, low-income, minority children and adherence may be even more problematic in this group. To reach inner-city, low-income, minority children, the school provides a logical access point. Many types of school-based self-management and educational interventions have been developed and tested. While these programs have shown improvements in knowledge and self-management behaviors, they have had only a minimal impact on asthma morbidity. Therefore, we propose to develop a school based supervised asthma therapy intervention to increase adherence to medication in low-income, minority children with asthma from an inner-city pediatric asthma clinic. We will use a randomized clinical trial of 250 children from an inner-city clinic to test the impact of school based supervised asthma therapy on asthma exacerbations. Our long-term collaborative relationships and current work within our city school systems provide a strong foundation for this proposal.

描述（由申请人提供）：儿童哮喘是儿童发病的重要原因。这种发病率大部分是可以预防的，因为它可以直接归因于缺乏对医疗方案的遵守。对大多数患者来说，不遵医嘱的后果是病情恶化。吸入皮质类固醇对哮喘发作有相当大的保护作用。然而，很少有孩子按照国家哮喘教育和预防计划指南的建议服用药物。因此，坚持用药对于最终降低发病率至关重要。哮喘发病率在市中心、低收入和少数民族儿童中较高，在这一群体中，坚持治疗可能更成问题。为了接触到市中心低收入的少数族裔儿童，学校提供了一个合乎逻辑的接入点。许多类型的以学校为基础的自我管理和教育干预已经开发和测试。虽然这些项目显示了知识和自我管理行为的改善，但它们对哮喘发病率的影响很小。因此，我们建议开发一种基于学校的监督哮喘治疗干预，以增加来自市中心儿科哮喘诊所的低收入少数民族哮喘儿童的药物依从性。我们将使用一项随机临床试验，对来自市中心诊所的250名儿童进行试验，以测试基于学校的监督哮喘治疗对哮喘恶化的影响。我们的长期合作关系和目前在我们城市学校系统内的工作为这个提议提供了坚实的基础。