Advanced Analysis of the Development of Alcohol Problems

描述(由申请人提供)：本K02续展建议书描述 三个主要目标：开发新的统计方法以更好地回答 酒精研究中与发展有关的实质性问题和 预防酒精问题，与酒精研究人员合作 对其数据进行高级统计分析，并传播关于 新的方法，以便酒精领域的其他人可以从中受益。 发展和发展研究的五个统计领域 将研究酒精问题的预防：混合数据分析， 分类和其他非正态数据分析、多层次数据分析、 缺失数据分析，以及纵向分析。在……范围内 纵向分析将研究三个主题：生存的延伸 分析、随机试验、电源和设计问题。与以下项目协作 研究人员对他们的酒精数据进行分析将涉及高级 对与酒精问题有关的几个纵向数据集的分析。 传播关于在该项目内制定的新方法的信息 将通过出版实质性的-和 以方法论为导向的文章，酒精和统计方面的演讲 会议、培训课程、参观酒精研究中心和主持 加州大学洛杉矶分校方法组的来访者。 计划开展两种主要类型的职业发展和培训活动 在K02范围内：关于与 酒精问题的发展和预防与高级统计学 训练。实质性培训的中心部分将通过以下方式进行 与酒精及相关领域的几位关键专家合作。

DESCRIPTION (provided by applicant): This K02 renewal proposal describes three major aims: To develop new statistical methods to better answer substantive questions in alcohol research related to the development and prevention of alcohol problems, to collaborate with alcohol researchers on advanced statistical analysis of their data, and to disseminate information on the new methods so that others in the alcohol fields can benefit from them. Five areas of statistics integral to the study of the development and prevention of alcohol problems will be studied: mixture data analysis, categorical and other non-normal data analysis, multilevel data analysis, missing data analysis, and longitudinal analysis. Within the area of longitudinal analysis three topics will be studied: Extensions of survival analysis, randomized trials, and power and design issues. Collaboration with researchers on the analysis of their alcohol data will involve advanced analyses of several longitudinal data sets concerned with alcohol problems. Dissemination of information on the new methods developed within the project will take place through the publication of substantively- and methodologically-oriented articles, presentations at alcohol and statistical meetings, training sessions, visits at alcohol research centers, and hosting visitors at my UCLA methods group. Two major types of career development and training activities are planned within the K02: Training on substantive research issues related to the development and prevention of alcohol problems and advanced statistical training. The central part of the substantive training will occur through collaboration with a few key experts in alcohol and related fields.