Examining genome wide gene expression changes during cardiac injury and regeneration

心脏病是澳大利亚人死亡的主要原因。心脏病发作后，失去跳动的心脏细胞会被永久性疤痕所取代，这限制了心脏的正常功能。斑马鱼能从心脏病发作中恢复过来。新的心脏细胞会生成，而不是形成疤痕。该项目将利用斑马鱼来识别促进心脏再生的新信号，并有可能应用于人类心脏，以逆转损伤后的损伤。

Heart attacks are the leading cause of death in Australia. Following a heart attack, the loss of beating heart cells is replaced with a permanent scar and this limits the heart from functioning properly. The zebrafish can uniquely recover from a heart attack. New heart cells are generated rather than scar formation. This project will use the zebrafish to identify new signals that promote heart regeneration and can potentially be applied in human hearts to reverse the damage following injury.