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Excitatory interneurons: a sensory amplifier for pathological pain

Excitatory interneurons: a sensory amplifier for pathological pain
兴奋性中间神经元:病理性疼痛的感觉放大器
批准号:
nhmrc : 1144638
负责人:
A/Pr Brett Graham
金额:
$43.94万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31

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中文摘要
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英文摘要
Changes to the nervous system during pathological pain remain poorly understood. This poses a barrier to new and more effective pain therapies. We have recently shown that a population of excitatory nerve cells, which express a protein called calretinin, form an amplifier network within the spinal cord that enhances pain signalling. This application will determine how calretinin-positive nerve cells contribute to pathological pain and can subsequently be targeted to provide pain relief.
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Excitatory interneurons: a sensory amplifier for pathological pain
  • 批准号:
    nhmrc : GNT1144638
  • 项目类别:
    Project Grants
  • 资助金额:
    $64.98万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Brett Graham
  • 依托单位:
Hypothalamic Control Of Motivated Behavior
  • 批准号:
    nhmrc : GNT1125478
  • 项目类别:
    Project Grants
  • 资助金额:
    $49.97万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Brett Graham
  • 依托单位:
Hypothalamic Control Of Motivated Behavior
  • 批准号:
    nhmrc : 1125478
  • 项目类别:
    Project Grants
  • 资助金额:
    $34.07万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Brett Graham
  • 依托单位:
Mechanisms underlying efferent feedback in the vestibular system
  • 批准号:
    nhmrc : GNT1105110
  • 项目类别:
    Project Grants
  • 资助金额:
    $49.15万
  • 财政年份:
    2016
  • 负责人:
    A/Pr Brett Graham
  • 依托单位:
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