Cochlear Implant--Auditory Function & Speech Perception

描述（由申请人提供）：本项目的目标是对接受电声联合刺激（EAS）的患者的言语、声音和音乐感知能力进行研究，并将言语、声音和音乐感知与声学听觉区域的潜在心理物理能力联系起来。将通过与6个目标相关的实验和分析来实现这一目标。目的1是通过评估听觉阈值和获得非线性耳蜗处理、频率选择性和时间分辨率的估计来表征植入前后残留听力患者的低频声学听力。目的2是评估单独的声刺激、单独的电刺激以及声电联合刺激对言语、声音和音乐识别测试的影响。目标3是确定低频声学听力的心理物理测量与言语、声音和音乐识别测量之间的关系。目的4是比较EAS患者、单侧植入患者和双侧植入患者在言语、声音和音乐识别方面的表现。目的5是评估相对于声学听觉区域中的纯音的刺激递送到电极的音高，并将电音高与耳蜗中电极位置的计算机化X线摄影评估相关联。目标6是进行滤波器频带到电极分配的研究，以评估（a）基于声电音调匹配（如目标5中）将滤波器频带分配到电极是否产生比滤波器频带的标准分配更好的语音识别，以及（B）对于最大水平的性能，声刺激和电刺激的低频表示中的重叠是否是必要的。

DESCRIPTION (provided by applicant): The goal of this project is to conduct a study of the speech, voice and music perception abilities of patients who hear with combined electric and acoustic stimulation (EAS) and to relate speech, voice and music perception to underlying psychophysical abilities in the region of acoustic hearing. The goal will be met through experiments and analyses relative to 6 aims. Aim 1 is to characterize low frequency acoustic hearing in patients with residual hearing before and after implantation by assessing auditory thresholds and by obtaining estimates of nonlinear cochlear processing, frequency selectivity and temporal resolution. Aim 2 is to assess the effects of acoustic stimulation alone, electric stimulation alone and combined acoustic and electric stimulation on tests of speech, voice and music recognition. Aim 3 is to determine the relationships among the psychophysical measures of low-frequency acoustic hearing and the measures of speech, voice and music recognition. Aim 4 is to compare the performance of EAS patients, patients with unilateral implants and patients with bilateral implants on measures of speech, voice and music recognition. Aim 5 is to assess the pitch of stimulation delivered to electrodes relative to that of pure tones in the region of acoustic hearing and to relate electrical pitch to computerized radiography assessment of electrode position in the cochlea. Aim 6 is to conduct studies of filter-band-to-electrode assignments in order to assess (a) whether assigning filter-bands to electrodes based on acoustic-electric pitch matching (as in Aim 5) produces better speech recognition than a standard assignment of filter bands and (b) whether overlap in representation of low frequencies by acoustic and electric stimulation is necessary for maximum levels of performance.