Improved Search Coil Method for Measuring Eye Movements

用于测量眼球运动的改进搜索线圈方法

• 批准号: 6929951
• 负责人: MARK J SHELHAMER
• 金额: $ 19.8万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6929951
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; clinical research; contact lens; eye movement disorders; eye movements; human subject; patient monitoring device; portable biomedical equipment; telemetry; vestibuloocular reflex

DESCRIPTION (provided by applicant): The investigators will develop a new device for the precise and convenient measurement of eye movements. The device is based on the existing and widely used wired scleral search coil technique, in which an annular contact lens with a small coil of wire is placed on the eye, and its orientation determined from the magnitude of the current induced in the coil by external magnetic fields. The new device uses a similar scleral contact lens on the eye, but the new lens has no wires leading from the eye coil to the associated electronics. Signals are induced in the eye coil, and detected from the eye coil, by a transmitter/receiver near the eye. The orientation of the lens and coil is determined from the received signal. An existing prototype system is the basis for further development of the new system, which will proceed along the following lines: 1) assessment of engineering design options with the existing system; 2) fabrication of new contact lenses with the appropriate coils embedded; 3) extension of the system to measure torsional eye movements as well as horizontal and vertical; 4) packaging as a stand-alone system that can be worn by the subject; 5) assessment of performance by video analysis of eye and lens motion. This new method retains the conventional wired coil's benefits of high resolution and accuracy, large range of movement, and complete three-dimensional measurement of orientation. The largest drawback of the conventional system is the wires that lead from the eye coils to the signal processing electronics. By eliminating these wires, several very significant advantages result. Subject comfort is greatly increased, as the external wiring leading from the eye often irritates the eyelid and causes annoying stimulation of the eyelashes. A greater range of experiments can be performed, since the placement of the head within the external magnetic fields becomes less restrictive; head-free experiments, such as those involving locomotion and self-generated movements become much more practical. Perhaps most importantly, breakage of the external wiring (the most common source of failure in current systems) is avoided. The "wireless" measurement system will be of tremendous benefit to both the research and the clinical communities. In particular, vestibular and oculomotor patients should tolerate the new coils much better than existing ones, allowing easier and more convenient recording of precise eye movements in a larger segment of this population, for whom the conventional coils are often intimidating and uncomfortable.

描述（由申请人提供）：研究者将开发一种新的设备，用于精确和方便地测量眼球运动。该设备基于现有的和广泛使用的有线巩膜探测线圈技术，其中具有小线圈的环形接触透镜被放置在眼睛上，并且其取向由外部磁场在线圈中感应的电流的大小确定。新设备在眼睛上使用类似的巩膜接触透镜，但是新的透镜没有从眼睛线圈到相关电子设备的电线。信号在眼睛线圈中被感应，并且通过眼睛附近的发射器/接收器从眼睛线圈检测。根据接收到的信号确定透镜和线圈的取向。现有的原型系统是进一步开发新系统的基础，新系统将沿着以下路线进行：1）评估现有系统的工程设计选项; 2）制造具有嵌入的适当线圈的新接触镜; 3）扩展系统以测量扭转眼球运动以及水平和垂直眼球运动; 4）包装为可由受试者佩戴的独立系统; 5）通过眼睛和透镜运动的视频分析来评估性能。这种新方法保留了传统有线线圈分辨率高、精度高、运动范围大、方位测量完整的优点。传统系统的最大缺点是从眼线圈到信号处理电子设备的导线。通过消除这些线，产生了几个非常显著的优点。受试者的舒适度大大提高，因为从眼睛引出的外部布线经常刺激眼睑并引起睫毛的恼人刺激。可以进行更大范围的实验，因为头部在外部磁场中的位置变得不那么受限制;没有头部的实验，例如涉及运动和自发运动的实验变得更加实用。也许最重要的是，避免了外部布线的断裂（当前系统中最常见的故障源）。“无线”测量系统将对研究和临床社区都有巨大的好处。特别是，前庭和眼科患者应该比现有的线圈更好地耐受新的线圈，允许更容易和更方便地记录该人群中更大部分的精确眼球运动，对他们来说，传统的线圈通常是令人生畏和不舒服的。