International Meeting on Gonadotropins

描述（由申请人提供）：拟于2004年秋季在格鲁吉亚大学的格鲁吉亚中心举行一次关于促性腺激素（异二聚体糖蛋白激素）、其G蛋白偶联受体和新型临床诊断应用的国际会议。 这次会议的目标是审查自1996年上次会议以来在这一领域取得的进展，并为适当开发最近发现的新诊断应用提出一些协商一致的建议。 令人兴奋的新发展包括激素及其受体的结构-功能关系的知识的进步，这些发现与临床观察的相关性，促性腺激素，特别是hCG的新功能，除了生殖生理学中的经典功能，以及促性腺激素的命名，unexpressed和更好的可比性的临床实验室测量的建议的发展。 主题将包括：促性腺激素及其受体的结构功能研究、信号转导、与促性腺激素相关的孤儿受体、促性腺激素及其亚型的测量、通过新标准和单位改进的临床测定相关性、hCG亚型测量在产前诊断和癌症诊断和治疗中的新临床应用。 会议将吸引来自学术机构、联邦实验室和制药公司的科学家和受训人员，以及医学界的研究/诊断人员。 组委会由活跃在促性腺激素领域的国际科学家组成，包括来自诊断试剂盒制造商的一些研究人员，以便基础研究进展能够迅速转化为临床应用，造福社会。 已与该领域的一家知名出版商安排出版一本专著，其中包括发言者和其他选定与会者撰写的同行审查论文。

DESCRIPTION (provided by applicant): An international conference is proposed to be held at the Georgia Center at the University of Georgia in the Fall 2004 on gonadotropins (heterodimeric glycoprotein hormones), their G protein-coupled receptors, and novel clinical diagnostic applications. The goals of this meeting are to review the progress in this field since the last such meeting in 1996 and to develop some consensus recommendations for proper development of new diagnostic applications deriving from recent discoveries. Exciting new developments include advances in knowledge of the structure-function relationships of the hormones and their receptors, correlation of these discoveries with clinical observations, novel functions of the gonadotropins, especially hCG, in additional to classical functions in reproductive physiology, and development of recommendations for nomenclature, unitage, and better comparability for clinical laboratory measurements of the gonadotropins. Topics will include: structure function studies of the gonadotropins and their receptors, signal transduction, orphan receptors related to gonadotropins, measurement of gonadotropins and their isoforms, improved clinical assay correlations through new standards and units, novel clinical applications of measurement of hCG isoforms in prenatal diagnosis and cancer diagnosis and treatment. The meeting will attract scientists and trainees from academic institutions, federal laboratories, and pharmaceutical firms, as well as research/diagnostic oriented members of the medical community. The organizing committee is comprised of an international group of scientists active in the gonadotropin field and includes some investigators from diagnostic kit manufacturers as well so that basic research progress can be rapidly translated into clinical applications for the general benefit of society. Publication of a monograph comprised of peer-reviewed papers written by speakers and other selected attendees at the meeting has been arranged with an established publisher in the field.