Exploring development and evolution of the maternal and infant skin microbiome

探索母婴皮肤微生物组的发育和进化

• 批准号: 2444179
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2444179
• 关键词: Exploring; development; evolution; maternal; infant

Human skin faces constant external challenge. While skin has evolved to combat insults such as infection and pollution a key element of its defence is the human microbiome, the first layer of protection. Despite the increasing recognition of the importance of the skin microbiome health there has been little investigation of the baby skin microbiome, and almost no investigation of the longitudinal development of that microbiome after birth.This project seeks to investigate the development and evolution of the human skin microbiome while gaining a greater understanding of the impact that microbial disturbances in early years can have on skin health. These insights will be essential to the formulation of the next generation of skin care products to maintain skin health across the life course.

人类皮肤面临着不断的外部挑战。虽然皮肤已经进化到可以对抗感染和污染等侵害，但其防御的一个关键要素是人类微生物组，这是第一层保护。尽管人们越来越认识到皮肤微生物组健康的重要性，但对婴儿皮肤微生物组的调查却很少，几乎没有对出生后微生物组的纵向发展进行调查。本项目旨在调查人类皮肤微生物组的发展和演变，同时更好地了解早期微生物干扰对皮肤健康的影响。这些见解对于下一代护肤品的配方至关重要，以在整个生命过程中保持皮肤健康。