A Mechanistic Approach to Understanding Human Circadian and Sleep Genetics BBSRC DTP DPhil in Interdisciplinary Bioscience DPhil Proposal Tatiana S. W

理解人类昼夜节律和睡眠遗传学的机械方法 BBSRC DTP 跨学科生物科学博士 DPhil 提案 Tatiana S. W

• 批准号: 2445633
• 金额: --
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2445633
• 关键词: Mechanistic; Approach; Understanding; Human; Circadian

Sleep is a universally conserved process in animals that is essential to life, yet its function and regulation remain poorly understood. By looking at natural variations in human sleep patterns and their associated genetics, it is possible to identify genes that may be involved in regulating aspects of sleep such as sleep duration. Additionally, this same method can be used to assess how the circadian system, the internal biological timing system, regulates sleep.Priorities AddressedBBSRC: Data driven biology, systems approaches to the biosciencesCross Council Priorities: Brain Science and Mental Health

睡眠是动物中普遍保守的过程，对生命至关重要，但其功能和调节仍然知之甚少。通过观察人类睡眠模式的自然变化及其相关的遗传学，有可能确定可能参与调节睡眠方面的基因，例如睡眠时间。此外，同样的方法可以用来评估昼夜节律系统，内部生物计时系统，如何调节睡眠。优先事项解决BBSRC：数据驱动的生物学，系统方法的生物科学交叉理事会优先事项：脑科学和心理健康