Exploiting increased autophagy in bronchial epithelial cells: a new therapeutic approach for chronic obstructive pulmonary disease (COPD)
Exploiting increased autophagy in bronchial epithelial cells: a new therapeutic approach for chronic obstructive pulmonary disease (COPD)
利用支气管上皮细胞自噬的增加：慢性阻塞性肺疾病（COPD）的新治疗方法
批准号：
nhmrc : GNT1099040
负责人：
Dr Eugene Roscioli
金额：
$72.42万
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2016
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2016-01-01 至 --
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英文摘要
COPD is incurable, a leading cause of death, and new therapies are urgently needed. Autophagy is a cell response to cell stress conditions, however increased autophagy is harmful. We will investigate the association of increased autophagy with COPD and smoking and evaluate therapies that can reduce autophagy, including zinc-related drugs and novel antibiotics that have been modified to lose their anti-bacterial activity.
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