Communication Intervention with Melanoma Families

与黑色素瘤家族的沟通干预

• 批准号: 6891059
• 负责人: DEBORAH J. BOWEN
• 金额: $ 62.25万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6891059
• 关键词: Internet; behavioral /social science research tag; cancer prevention; cancer registry /resource; cancer risk; clinical research; communication; cost effectiveness; dosage; environmental exposure; family genetics; family structure /dynamics; genetic counseling; genetic susceptibility; health behavior; human subject; interactive multimedia; interpersonal relations; melanoma; neoplasm /cancer education; perception; quality of life; self examination; solar radiation; statistics /biometry

DESCRIPTION (provided by applicant): Melanoma is a relatively common cancer, with stable or rising rates in the United States. Recent studies have identified genetics as an important contributor to risk, in addition to the well-established environmental risk factor of sun exposure. Self-examination is a potential method of identifying melanoma early enough to treat, and reducing sun exposure, especially in childhood, is a specific method of reducing risk of melanoma incidence. Both of these behavioral risk reduction behaviors need to be promoted, especially in individuals at familial risk for melanoma. We propose to identify cases of melanoma via an existing population-based registry to deliver behavioral and communications messages to the case and family members. We will randomize families to receive a Web-based intervention to help them through the experience of melanoma diagnosis, treatment, and recovery by emphasizing communications, support, information about risk, and changing health behaviors related to risk. This model of cancer-related behavior change intervention is potentially relevant to many different forms of familial cancer. The main aim of the randomized trial is to improve the sun exposure and self-examination behaviors of melanoma cases, first degree relatives, and the parents of children 0-18 via an intervention delivered through interactive electronic communication methods. Secondary intervention aims include determining the effects of this intervention on secondary outcomes from our behavioral model, identifying characteristics of user subgroups of relatives and relating these to outcomes, examining the acceptability of this intervention package, and determining the relationship between dose of intervention and effect of intervention. Aims addressing basic issues in communications are to identify perceptions and understanding of melanoma risk and family communication in melanoma cases, first degree relatives and parent and children, and relation to exposure related risk, general health risk, and health-related quality of life and to determine the effects of risk information framing on intentions to perform screening and sun exposure reduction behaviors.

描述（由申请人提供）：黑色素瘤是一种相对常见的癌症，在美国的发病率稳定或上升。最近的研究发现，除了阳光照射这一公认的环境风险因素外，遗传学也是风险的重要因素。自我检查是一种早期发现黑色素瘤的潜在方法，以治疗，减少阳光照射，特别是在儿童时期，是降低黑色素瘤发病风险的一种具体方法。这两种降低风险的行为都需要推广，特别是在有黑色素瘤家族风险的个体中。我们建议通过现有的基于人群的登记来识别黑色素瘤病例，以向病例和家庭成员提供行为和通信信息。我们将随机分配家庭接受基于网络的干预，通过强调沟通，支持，风险信息和改变与风险相关的健康行为，帮助他们通过黑色素瘤诊断，治疗和康复的经验。这种癌症相关行为改变干预模式可能与许多不同形式的家族性癌症有关。 这项随机试验的主要目的是通过交互式电子通信方法进行干预，改善黑色素瘤病例、一级亲属和0-18岁儿童的父母的阳光照射和自我检查行为。二级干预的目的包括确定这种干预对我们的行为模型的二级结果的影响，确定用户亲属亚组的特征，并将其与结果相关联，检查这种干预方案的可接受性，并确定干预剂量和干预效果之间的关系。解决沟通中的基本问题的目的是确定对黑色素瘤风险和黑色素瘤病例中的家庭沟通、一级亲属、父母和子女的认知和理解，以及与暴露相关风险、一般健康风险和健康相关生活质量的关系，并确定风险信息框架对进行筛查和减少阳光照射行为的影响。