Sensory Re-training following Orthognathic Surgery
Sensory Re-training following Orthognathic Surgery
批准号:
6891389
负责人:
CEIB PHILLIPS
金额:
$34.56万
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-07-15 至 2008-05-31
中文摘要
描述:(申请人提供)面部感觉异常
对患者的口腔行为产生负面影响,并可能对
如果改变的感觉持续存在,患者的生活质量。许多患者患有
异常感觉保留了一些感觉功能,不会发展为慢性
疼痛,而对于这些人来说,目前没有基于证据的
非侵入性治疗。这个项目的目标是评估感官
再培训,一种康复疗法,提供了巨大的潜力
无论原因如何,感觉功能受损的患者。这
行为疗法已经在临床上取得了很大的成功
自20世纪70年代以来,手部损伤患者。再培训似乎加强了中央
从受损的感觉神经到大脑的冲动的重组
皮层,以便改变的感觉信号可以被解释和翻译
转化为有功能意义的运动功能。
感觉再训练将被比作安慰剂张开嘴巴的练习
单盲、随机双臂平行分组分层麻醉临床研究
试验,以正颌外科患者为研究对象。正颌外科
患者为评估新的康复治疗提供了一个不妥协的模式
治疗。这些健康的患者接受了矫正牙面畸形的治疗,
目前正在接受手术,没有神经感觉损伤,但仍是常规的
手术后面部感觉发生实质性变化
程序。感觉再训练的效果将用三种方法进行评估。
结果类型:以患者为中心的措施,以评估
术后感觉改变的负面影响及所需恢复时间
达到很小或没有负面影响;神经感官行为评估
患者学习触觉和其他提示的能力
以及传统的神经感觉接触阈值测量
评估实际赤字。我们的主要关注点是病人的
对感觉变化对日常生活的负面影响的感知。
英文摘要
DESCRIPTION: (provided by the applicant) Abnormal facial sensation has a
negative impact on patient's oral behaviors and may adversely affect a
patient's quality of life if the altered sensation persists. Many patients with
abnormal sensations retain some sensory function and do not develop chronic
pain, and for those individuals there are no currently evidence-based
noninvasive therapies. The goal of this project is to evaluate sensory
re-training, a rehabilitative therapy that offers significant potential for
patients who experience impaired sensory function regardless of the cause. This
behavior therapy approach has been used with substantial clinical success with
hand injury patients since the 1970s. Re-training appears to enhance central
reorganization of the impulses from an injured sensory nerve to the cerebral
cortex so that the altered sensory signals can be interpreted and translated
into functionally meaningful motor functions.
Sensory re-training will be compared to a placebo jaw-opening exercise in a
single blind, randomized two-arm parallel group stratified block clinical
trial, using orthognathic surgery patients as subjects. Orthognathic surgery
patients offer an uncompromised model for the evaluation of new rehabilitative
therapies. These healthy patients, treated to correct dentofacial deformity,
present for surgery with no neurosensory impairment, but yet routinely
experience substantial alterations in facial sensation following the surgical
procedure. The effcts of sensory re-training will be evaluated using three
types of outcomes: patient-centered measures to assess the magnitude of the
negative effect of altered sensation after surgery and the recovery time needed
to reach little or no negative effect; neurosensory behavior measures to assess
the patient's ability to learn alternate cues for touch perception and
discrimination; and a conventional neurosensory contact threshold measure to
assess the actual deficit. Our primary focus will be on the patient's
perception of the negative impact of altered sensation on daily life.
期刊论文(9)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1111/j.1600-0528.2010.00583.x
发表时间:
2011-04
期刊:
Community dentistry and oral epidemiology
影响因子:
2.3
作者:
[Preisser JS, Phillips C, Perin J, Schwartz TA]
通讯作者:
Schwartz TA
DOI:
10.1111/j.1601-6343.2010.01493.x
发表时间:
2010-08
期刊:
Orthodontics & craniofacial research
影响因子:
3.1
作者:
[C. Phillips;S. H. Kim;M. Tucker;T. Turvey]
通讯作者:
C. Phillips;S. H. Kim;M. Tucker;T. Turvey
DOI:
10.1016/j.cxom.2010.11.006
发表时间:
2011-03
期刊:
Atlas of the oral and maxillofacial surgery clinics of North America
影响因子:
--
作者:
[Phillips, Ceib, Blakey, George 3rd, Essick, Greg K]
通讯作者:
Essick, Greg K
DOI:
10.1111/j.1365-2842.2010.02176.x
发表时间:
2011-07
期刊:
Journal of oral rehabilitation
影响因子:
2.9
作者:
[Phillips C, Essick G]
通讯作者:
Essick G
Core--Clinical and biometric
-
批准号:6876998
-
项目类别:
-
资助金额:$31.24万
-
财政年份:2004
-
负责人:CEIB PHILLIPS
-
依托单位:
Sensory Re-training following Orthognathic Surgery
-
批准号:6395331
-
项目类别:
-
资助金额:$34.56万
-
财政年份:2001
-
负责人:CEIB PHILLIPS
-
依托单位:
Sensory Re-training following Orthognathic Surgery
-
批准号:6516647
-
项目类别:
-
资助金额:$34.56万
-
财政年份:2001
-
负责人:CEIB PHILLIPS
-
依托单位:
Sensory Re-training following Orthognathic Surgery
-
批准号:6607361
-
项目类别:
-
资助金额:$34.56万
-
财政年份:2001
-
负责人:CEIB PHILLIPS
-
依托单位:
Sensory Re-training following Orthognathic Surgery
-
批准号:6758504
-
项目类别:
-
资助金额:$34.56万
-
财政年份:2001
-
负责人:CEIB PHILLIPS
-
依托单位:
PSYCHOSOCIAL VS CLINICAL RESPONSES--ORTHOGNATHIC SURGERY
-
批准号:2131008
-
项目类别:
-
资助金额:$24.83万
-
财政年份:1995
-
负责人:CEIB PHILLIPS
-
依托单位:
PSYCHOSOCIAL VS CLINICAL RESPONSES--ORTHOGNATHIC SURGERY
-
批准号:2458601
-
项目类别:
-
资助金额:$25.13万
-
财政年份:1995
-
负责人:CEIB PHILLIPS
-
依托单位:
PSYCHOSOCIAL VS CLINICAL RESPONSES--ORTHOGNATHIC SURGERY
-
批准号:2749318
-
项目类别:
-
资助金额:$25.99万
-
财政年份:1995
-
负责人:CEIB PHILLIPS
-
依托单位:
PSYCHOSOCIAL VS CLINICAL RESPONSES--ORTHOGNATHIC SURGERY
-
批准号:2131007
-
项目类别:
-
资助金额:$24.87万
-
财政年份:1995
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability Following Orthognathic Surgery
-
批准号:8043632
-
项目类别:
-
资助金额:$60.95万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability following Orthognathic Surgery
-
批准号:7067600
-
项目类别:
-
资助金额:$41.04万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability Following Orthognathic Surgery
-
批准号:7655767
-
项目类别:
-
资助金额:$56.92万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability following Orthognathic Surgery
-
批准号:6886813
-
项目类别:
-
资助金额:$41.12万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability Following Orthognathic Surgery
-
批准号:7802844
-
项目类别:
-
资助金额:$59.04万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability Following Orthognathic Surgery
-
批准号:8436285
-
项目类别:
-
资助金额:$54.53万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Influences on Stability Following Orthognathic Surgery
-
批准号:8225399
-
项目类别:
-
资助金额:$59.93万
-
财政年份:1979
-
负责人:CEIB PHILLIPS
-
依托单位:
Core--Clinical and biometric
-
批准号:7259498
-
项目类别:
-
资助金额:$36.31万
-
财政年份:--
-
负责人:CEIB PHILLIPS
-
依托单位:
Core--Clinical and biometric
-
批准号:7476411
-
项目类别:
-
资助金额:$36.18万
-
财政年份:--
-
负责人:CEIB PHILLIPS
-
依托单位:
Core--Clinical and biometric
-
批准号:7112906
-
项目类别:
-
资助金额:$34.24万
-
财政年份:--
-
负责人:CEIB PHILLIPS
-
依托单位:
海外基金