Parkinson's Disease Neuroprotection Clinical Trial

帕金森病神经保护临床试验

• 批准号: 6797316
• 负责人: GEORGE F WOOTEN
• 金额: $ 2.96万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6797316
• 关键词: Parkinson' s disease; chemoprevention; clinical research; cooperative study; human subject; human therapy evaluation; medical outreach /case finding; nervous system disorder chemotherapy; neuroprotectants; patient oriented research

DESCRIPTION (provided by applicant): This is an application for a Clinical Center for the Parkinson's Disease Neuroprotection Trial from the Department of Neurology at the University of Virginia in response to RFA-NS-02-010. We have a clinical staff of four movement disorder subspeciality neurologists, a nurse coordinator, an administrative coordinator, and an information and referral coordinator. Over the past 10 years, our team has enrolled 445 subjects in clinical trials with 413 subjects completing the protocol. Our diagnostic accuracy and interrater reliability are documented objectively and are excellent. We have been highly productive of scholarly publications with 26-refereed publications on clinical aspects of PD in the past 5 years. Over the past six years we have ascertained 150 patients with a clinical diagnosis of Parkinson's disease (PD) who were receiving no symptomatic therapy. We have excellent alliances with multiple patient support groups and both referring neurologists and primary care physicians throughout the state of Virginia. Our team is experienced, productive, and fully able to meet the requirements to become a Clinical Cente for the Parkinson's Disease Neuroprotection Trial.

描述（由申请人提供）：这是弗吉尼亚大学神经内科临床中心针对RFA-NS-02-010提出的帕金森病神经保护试验的申请。我们的临床工作人员有四名运动障碍亚专科神经科医生，一名护士协调员，一名行政协调员，以及一名信息和转诊协调员。在过去的10年里，我们的团队已经招募了445名受试者进行临床试验，其中413名受试者完成了方案。我们的诊断准确性和相互间的可靠性是客观记录的，并且是优秀的。在过去的5年里，我们发表了26篇关于PD临床方面的学术论文。在过去的六年中，我们已经确定了150例临床诊断为帕金森病（PD）的患者，他们没有接受任何对症治疗。我们与多个患者支持小组以及弗吉尼亚州的转诊神经科医生和初级保健医生建立了良好的联盟。我们的团队经验丰富，富有成效，完全能够满足成为帕金森病神经保护试验临床中心的要求。