Parkinson's Disease Neuroprotection Clinical Trial

描述(由申请人提供)：这是弗吉尼亚大学神经病学系针对RFA-NS-02-010提出的帕金森氏病神经保护试验临床中心的申请。我们有四名运动障碍亚专业神经科医生的临床工作人员，一名护士协调员，一名行政协调员，以及一名信息和转诊协调员。在过去的10年里，我们的团队已经招募了445名受试者进行临床试验，其中413名受试者完成了方案。我们的诊断准确性和评分员之间的可靠性客观地记录在案，并且非常出色。在过去的5年里，我们的学术出版物非常多产，有26篇关于帕金森病临床方面的参考文献。在过去的六年里，我们确定了150名临床诊断为帕金森氏病(PD)的患者，他们没有接受对症治疗。我们与多个患者支持团体以及整个弗吉尼亚州的转诊神经科医生和初级保健医生都有很好的联盟。我们的团队经验丰富、富有成效，完全能够满足成为帕金森氏病神经保护试验临床中心的要求。

DESCRIPTION (provided by applicant): This is an application for a Clinical Center for the Parkinson's Disease Neuroprotection Trial from the Department of Neurology at the University of Virginia in response to RFA-NS-02-010. We have a clinical staff of four movement disorder subspeciality neurologists, a nurse coordinator, an administrative coordinator, and an information and referral coordinator. Over the past 10 years, our team has enrolled 445 subjects in clinical trials with 413 subjects completing the protocol. Our diagnostic accuracy and interrater reliability are documented objectively and are excellent. We have been highly productive of scholarly publications with 26-refereed publications on clinical aspects of PD in the past 5 years. Over the past six years we have ascertained 150 patients with a clinical diagnosis of Parkinson's disease (PD) who were receiving no symptomatic therapy. We have excellent alliances with multiple patient support groups and both referring neurologists and primary care physicians throughout the state of Virginia. Our team is experienced, productive, and fully able to meet the requirements to become a Clinical Cente for the Parkinson's Disease Neuroprotection Trial.