Vanderbilt Center for Education/Research on Theraputics

描述：（由申请人提供）：范德比尔特治疗学教育和研究中心（CERT）的延续被提议作为国家合作的一部分，以系统地改进药物治疗。Vanderbilt CERT的主题是在医疗补助和退伍军人健康管理人群中鼓励最佳治疗，这些人群特别容易受到次优药物治疗的影响，由于各种原因在研究中代表性不足，并且受到可能对治疗产生不利影响的管理护理政策的影响。CERT重点关注的弱势群体包括发育中的胎儿、幼儿、低收入母亲、非洲裔美国人和其他少数民族、精神和身体残疾者、慢性病患者、老年人和养老院的人。范德比尔特CERT通过与我们的合作伙伴一起开展跨学科项目来实现其使命，这些项目有以下4个具体目标：

DESCRIPTION: (PROVIDED BY APPLICANT):Continuation of the Vanderbilt Center for Education and Research in Therapeutics (CERT) is proposed as part of a national collaboration to systematically improve pharmacotherapy. The theme of the Vanderbilt CERT is Encouraging Optimal Therapeutics in Medicaid and Veteran's Health Administration Populations, populations particularly vulnerable to suboptimal pharmacotherapy, underrepresented in research for a variety of reasons, and affected by managed care policies that may adversely affect therapeutics. Vulnerable groups encompassed by the CERT focus include the developing fetus, young children, low-income mothers, African Americans and other minorities, persons with mental and somatic disabilities, the chronically ill, the elderly, and persons in nursing homes. The Vanderbilt CERT realizes its mission by conducting interdisciplinary projects in conjunction with our partners that have the following 4 specific aims: 1. Improve the knowledge base for therapeutics by conducting studies of drug effects;2. Identify suboptimal provider or patient therapeutic practices;3. Conduct focused educational programs to improve therapeutics;4. Evaluate the impact of health care payer policies that may affect therapeutics. In its first three years, the Vanderbilt CERT has created an administrative infrastructure, organized 4 thematic investigator groups, and developed a collaborative network with 12 faculty. It has established strong partnerships with the State of Tennessee, the Tennessee Quality Improvement Organization, the Veteran's Administration Tennessee Valley Healthcare System and Geriatric Research, Education and Clinical Center, and the Food and Drug Administration. It has conducted 25 core projects that to date have resulted in 14 publications, 7 manuscripts under review, and 4 in preparation; and has 51 leveraged publications. In the upcoming cycle, the CERT will conduct 10 core projects and 3 partner-oriented, educational outreach/service activities. The multi-disciplinary projects include 7 research studies designed to inform provider and patient decision making in areas of clinical controversy and 3 educational programs underpinned by evidence-based guidelines and designed to reduce inappropriate variations in care. The projects include substantial representation of women, minorities, and children; and focus on high-cost disease states that are important to Medicaid, Medicare, and other federal health programs.