Exercise to Aid Smoking Cessation in Adolescent Girls

运动帮助青春期女孩戒烟

基本信息

批准号：
7058557
负责人：
Melissa A Napolitano
金额：
$ 7.26万
依托单位：
MIRIAM HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-30 至 2006-07-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): Approximately 22% of youth currently smoke cigarettes despite the increased risk of cancer and cardiovascular disease associated with cigarette use. Tobacco use continues to be the leading, preventable cause of mortality among US adults. Research has shown that those who smoke their first cigarette between the ages of 14-26 are more likely to become nicotine dependent, and, therefore, more resistant to smoking cessation efforts, than those initiating smoking at a later age. Although the smoking prevalence among girls declined in the 1970's and 1980's, the current smoking rates among high school girls has held constant from 1998 to 2000. Despite the negative health consequences associated with smoking, weight concerns and fear of weight gain have been shown to be associated with the uptake of smoking in girls. Alternatively, exercise has been shown to be a positive health behavior, and can provide the same perceived benefits of smoking: self-esteem, relaxation, weight management. In previous trials in adult women, vigorous intensity exercise has been shown to be effective for aiding with smoking cessation. Therefore, this study will adapt the efficacious group-based cognitive behavioral smoking cessation treatment plus exercise to meet the needs of adolescent girls. This project will consist of two phases. In Phase I of this project, 4 focus groups will be conducted (each consisting of 8-10 adolescent girls) to adapt the intervention. Adaptations will include making the materials, intervention content, and language age-appropriate and relevant for youth. Phase II of the project will consist of a randomized pilot study in which 40 adolescent girls will be randomly assigned to: a) standard cognitive-behavioral smoking cessation plus exercise (CBT+Exercise) or b) standard cessation with equal contact time (Standard+Contact). The sample will be recruited, treated for 12 weeks and followed for 3 months. Smoking cessation outcome (continuous abstinence) will be validated by saliva cotinine. Exercise adherence will be validated by attendance at supervised sessions, and objective monitoring. Secondary analysis, of proposed theoretical mediators of behavior change will be conducted, including weight concerns and self-efficacy. The primary hypothesis is that girls in the CBT+Exercise group will have higher quit rates than girls in the Standard+Contact group. In summary, we seek to:1) conduct the formative work to adapt the cessation materials and exercise protocol from a focus on adult women to adolescent girls, and 2) conduct a small randomized pilot trial to determine the preliminary efficacy of the intervention in a sample of adolescent girls. Therefore, this study will serve as a pilot for a larger clinical trial. Successful smoking cessation in adolescent girls could contribute to the future reduction of chronic disease mortality in this group.

描述（由申请人提供）：尽管与使用香烟有关的癌症风险增加了，但目前约有22％的青年目前吸烟。烟草的使用仍然是美国成年人死亡的主要原因。研究表明，与那些在后来的年龄启动吸烟相比，那些在14-26岁之间吸烟的人更有可能成为尼古丁依赖性，因此对吸烟努力的抵抗力更大。尽管在1970年代和1980年代，女孩的吸烟患病率在1970年代和1980年代下降，但从1998年到2000年，当前的高中女生吸烟率一直保持不变。尽管与吸烟有关，但与吸烟相关的负面影响，体重的担忧和对体重增加的恐惧却与女孩吸烟有关。另外，运动已被证明是一种积极的健康行为，可以提供吸烟的相同益处：自尊，放松，体重管理。在成年妇女的先前试验中，已证明强度的强度运动可有效帮助戒烟。因此，这项研究将适应有效的基于群体的认知行为戒烟治疗以及运动以满足青春期女孩的需求。该项目将由两个阶段组成。在该项目的第一阶段，将进行4个焦点小组（每个组成8-10个青春期女孩）以适应干预措施。适应将包括制作材料，干预内容以及适合年龄的材料，与青年人相关。该项目的第二阶段将包括一项随机试验研究，其中40个青春期女孩将被随机分配给：a）标准的认知行为戒烟戒烟加上运动（CBT+运动）或b）具有相同接触时间的标准戒烟（标准+接触）。样本将招募，处理12周，然后进行3个月。唾液cotinine将验证戒烟结果（连续禁欲）。运动依从性将通过有监督的会议和客观监控来验证。将对行为改变的理论调解人进行二次分析，包括体重关注和自我效能。主要假设是，CBT+运动组中的女孩的退出率将比标准+接触组中的女孩高。总而言之，我们寻求：1）进行形成性的工作，以使戒烟材料和运动方案从对成年女性的关注到青春期女孩，以及2）进行一项小型随机试验试验，以确定在青春期女孩样本中干预的初步疗效。因此，这项研究将作为大型临床试验的试点。青少年女孩的成功戒烟可能会导致该组的慢性疾病死亡率的未来降低。