BREAST CANCER SURVEILLANCE RESEARCH IN NORTH CAROLINA

北卡罗来纳州乳腺癌监测研究

• 批准号: 6796260
• 负责人: BONNIE C YANKASKAS
• 金额: $ 81.3万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6796260
• 关键词: Native Americans; bioimaging /biomedical imaging; breast neoplasms; cancer registry /resource; cancer risk; clinical research; community health services; cooperative study; diagnosis quality /standard; female; health services research tag; human subject; mammography; mass screening; women' s health

The objective of the CMR competitive renewals is to continue our original aims to continue to collect community-based mammography and pathology data for studying the patterns and outcomes of screening mammography and pathology data for studying the patterns and outcomes of screening mammography practice in North Carolina. Mammography and pathology databases have been developed which allow linking of screening mammography assessments with cancer outcomes. Data is being collected directly from mammography facilities including demographic data, breast history data, reason for and findings on the screening mammogram, data on other radiologic studies necessary to resolve the screening assessment , and recommendations for follow-up. The pathology data from the NC Central Cancer Registry is received on a fast report system (weekly) for pathology diagnosed in 39 counties where the study now is active, and on an annual basis for the entire state. We will also continue our building of a special registry for Native American women, beginning with the Lumbee women in southern NC. This project is part of the National Breast Cancer Surveillance Consortium and has met the data requirements for participation in this group. Additional objectives and a special project that are proposed include: 1 To expand our Native American project: to include a mammography registry for all Native American women in NC; to create a breast cancer registry for Lumbee women; and to test the feasibility of a breast tissue bank for Native American women in NC: 2 To conduct special surveys for collection of risk factor data that becomes of interest over the grant period, as an alternative to expanding the routine data collection in the mammography practices and 3. To continue our study of false negative screening mammography: to establish standards for acceptable rates of false negatives in the community; to understand the causes of missed cancers incommunity practice, and to develop an educational model to use the data from the film review process for continuing education for the participating radiologists. The additional special project is an analytic project to study the effect of variations in practice and radiologist interpretation of breast density on assessing breast density and screening mammography performance.

CMR竞争性更新的目的是继续我们最初的目标，即继续收集基于社区的乳腺X射线摄影和病理学数据，以研究筛查性乳腺X射线摄影的模式和结局，并收集病理学数据，以研究北卡罗来纳州筛查性乳腺X射线摄影实践的模式和结局。 已经开发了乳房X线摄影和病理学数据库，可以将筛查性乳房X线摄影评估与癌症结果联系起来。直接从乳房X线摄影设施收集数据，包括人口统计学数据、乳房病史数据、筛查乳房X线摄影的原因和结果、解决筛查评估所需的其他放射学研究数据以及随访建议。 来自NC中央癌症登记处的病理学数据通过快速报告系统（每周）接收，用于在39个县诊断的病理学，其中研究目前正在进行中，并且每年在整个州进行。 我们还将继续为美洲土著妇女建立一个特别登记册，首先从北卡罗来纳州南部的Lumbee妇女开始。 该项目是国家乳腺癌监测联盟的一部分，并满足了参加该小组的数据要求。1.扩大我们的美洲原住民项目：为北卡罗来纳州的所有美洲原住民妇女建立乳房X线摄影登记处;为Lumbee妇女建立乳腺癌登记处;并为北卡罗来纳州的美洲原住民妇女测试乳腺组织库的可行性：2.开展特别调查，收集补助期内感兴趣的风险因素数据，作为扩大乳房X光检查实践中常规数据收集的替代方法; 继续我们对乳腺X线筛查假阴性的研究：建立社区可接受的假阴性率标准;了解社区实践中漏诊癌症的原因，并开发一种教育模式，使用胶片审查过程中的数据对参与的放射科医生进行继续教育。另一个特别项目是一个分析项目，研究实践中的变化和放射科医生对乳腺密度的解释对评估乳腺密度和筛查乳腺X线摄影性能的影响。