Carolina Mammography Registry

描述（由申请人提供）：本提案是对美国国家癌症研究所RFA CA-05 - 502的回应，旨在支持基础设施的持续建设和维护，该基础设施已成为卡罗莱纳乳腺X线摄影登记处（CMR），作为乳腺癌监测联盟（BCSC）的一部分。BCSC是一个由七个乳腺X线摄影登记中心组成的协作网络，与病理学和肿瘤登记中心有联系。我们建议继续为北卡罗来纳州的一个地区开展《公路货运公约》的工作。将直接从乳腺X线摄影机构的女性和专业人员处收集基于实践的前瞻性数据，包括：人口统计学数据、乳腺病史数据、家族史、激素使用、筛查性乳腺X线摄影的原因和结果、解决筛查评估所需的其他成像研究数据以及随访建议。将从多个来源前瞻性收集病理学数据，包括直接从乳腺X射线摄影机构、快速病例报告系统和NC中央癌症登记处的所有乳腺癌记录的年度完整电子下载。随着知情同意的增加，以及进行特殊调查的能力，CMR将能够提供数据，以提高研究乳腺癌筛查、诊断、治疗和生存的能力。CMR中的数据代表了北卡罗来纳州人口的多样性和乳腺X射线摄影设施的多样性。所有数据将与（BCSC）的统计协调中心共享，以便由包括BCSC在内的登记研究的研究者和外部研究者进行汇总分析。将努力提高CMR和BCSC在北卡罗来纳州的知名度，以加强对研究、规划和教育数据的利用。

DESCRIPTION (provided by applicant): This proposal is in response to RFA CA-05-502 from the National cancer Institute, to support continued building and maintenance of the infrastructure that has become the Carolina Mammography Registry (CMR), as part of the Breast Cancer Surveillance Consortium (BCSC). The BCSC is a collaborative network of seven mammography registries with linkages to pathology and tumor registries. We propose to continue the work of CMR for a region of North Carolina. Prospective practice-based data will be collected directly from women and professionals in mammography facilities including: demographic data, breast history data, family history, hormone use, reason for and findings on the screening mammogram, data on other imaging studies necessary to resolve the screening assessment, and recommendations for follow-up. The pathology data will be collected prospectively from several sources including directly from mammography facilities, from a rapid case reporting system and annual complete electronic download of all breast cancer records from the NC Central Cancer Registry. With the addition of informed consent, and the ability to do special surveys, CMR will be able to contribute data to enhance the ability to study screening, diagnosis, treatment and survival for breast cancer. The data in CMR represents the diversity of the population of North Carolina and the diversity of the mammography facilities. All data will be shared with the Statistical Coordinating Center of the (BCSC) for pooled analyses by the investigators of the Registries comprising BCSC and outside investigators. Efforts will be made to increase the visibility of both CMR and the BCSC in North Carolina, to enhance use of the data for research, planning and education.