课题基金 / 基金详情

CORE--MYOCARDIAL CELL BIOLOGY AND VIRAL VECTOR FACILITY

CORE--MYOCARDIAL CELL BIOLOGY AND VIRAL VECTOR FACILITY
核心——心肌细胞生物学和病毒载体设施
批准号：
7098691
负责人：
Kirk U Knowlton
金额：
$15.69万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
项目状态：
已结题
起止时间：
2005-08-01 至 2007-07-31
来源：
https://reporter.nih.gov/project-details/7098691
关键词：
Adenoviridaeadeno associated virus groupbiomedical facilitycardiac myocytescell biologylaboratory mouselaboratory ratmyocardiumtissue /cell culturetransfectiontransfection /expression vector

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中文摘要
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英文摘要
DESCRIPTION (provided by applicant): Each of the projects in the program will utilize the Cell Biology Core Unit, which is designed to: 1) to provide purified cultures of neonatal rat ventricular myocardial cells and related techniques for gene transfer in these cells; 2) to provide purified mouse adult and neonatal ventricular muscle cells from various transgenic lines for analysis; 3) to generate and utilize recombinant adenoviral vectors for gene transfer in neonatal rat, adult and neonatal mouse myocardial cells, and for gene transfer into intact muscle for various projects in the program; and 4) to generate recombinant adeno-associated viral vectors for gene transfer in intact muscle.
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Adhesion Molecules of the Intercalated Disc in Cardiomyopathy
Administative Core
Adhesion Molecules of the Intercalated Disc in Cardiomyopathy
Administative Core