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Cognitive and Pharmacotherapy for Suicidal Adolescents

自杀青少年的认知和药物治疗

基本信息

批准号：
6876164
负责人：
STEPHANIE S DANIEL
金额：
$ 14.93万
依托单位：
WAKE FOREST UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
起止时间：
2001-04-01 至 2007-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6876164
关键词：
adolescence (12-20)behavioral /social science research tag clinical depression clinical research clinical trials cognitive behavior therapy combination therapy data collection methodology /evaluation education human subject human therapy evaluation interview mental disorder chemotherapy mental disorder diagnosis outcomes research social support network statistics /biometry suicide

项目摘要

DESCRIPTION (provided by applicant): This application for a career development award describes a plan for training and research in the area of clinical trials among children and adolescents, and will allow the candidate to pursue a program of research examining the efficacy of two different combinations of treatments for depressed, suicidal adolescents. The primary objective of this development award is for the candidate to gain expertise as an independent investigator in psychiatric clinical trials, particularly with children and adolescents. On-site mentoring for this development award will be provided by Dr. David Goldston (primary mentor) and by Dr. Curt Furberg (mentor in clinical trials methodology). External mentors for this development award include Drs. John March and John Curry (Duke University Medical Center). External consultants for this development award include Drs. David Brent, Maria Kovacs, Graham Emslie and Thomas Ellis. The research study described in this application is designed to examine the feasibility and efficacy of two different combinations of treatment (combined cognitive-behavioral therapy and pharmacotherapy vs. combined supportive therapy and education and pharmacotherapy) for depressed, suicidal adolescents. A small randomized contolled trial will be used to test the hypothesis that combined cognitive-behavioral therapy and pharmacotherapy will be more efficacious than combined supportive therapy education and pharmacotherapy in decreasing adolescents' depressive symptoms and suicidal behaviors (including suicidal ideation).

描述（由申请人提供）：此职业发展申请该奖项描述了临床试验领域的培训和研究计划在儿童和青少年中，并将允许候选人追求一个一项研究计划，检查两种不同组合的功效，治疗抑郁有自杀倾向的青少年这项工作的主要目的是发展奖是为候选人获得专业知识，作为一个独立的精神病临床试验研究者，特别是儿童和青少年。本次开发奖的现场指导将由大卫戈德斯通博士（主要导师）和博士Curt Furberg（临床导师试验方法）。这一发展奖的外部导师包括博士。 John March和John咖喱（杜克大学医学中心）。外部该开发奖的顾问包括大卫布伦特，玛丽亚科瓦奇，格雷厄姆·埃姆斯利和托马斯·埃利斯。本文中描述的研究应用程序旨在研究两种方法的可行性和有效性不同的治疗组合（联合认知行为治疗和药物治疗与联合支持治疗和教育，药物治疗）的抑郁症，自杀的青少年。一个小的随机对照试验将用于检验假设，认知行为疗法和药物疗法将比联合支持治疗教育和药物治疗，青少年的抑郁症状和自杀行为（包括自杀构思）。