Insertable Imaging and Effector Platform for Surgery

用于手术的可插入成像和效应器平台

• 批准号: 7027939
• 负责人: DENNIS LEE FOWLER
• 金额: $ 22.02万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-06 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7027939
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; image enhancement; image guided surgery /therapy; laparoscopy; miniature biomedical equipment; robotics; swine

DESCRIPTION (provided by applicant): We are proposing to design and construct small, mobile, multi-function platforms that can be placed inside a body cavity to assume some of the tasks associated with minimal access surgery. Motivated by limitations of current laparoscopic imaging devices, we propose a team of clinical minimal access surgeons and robotics researchers who will develop and test an initial micro robot that would include an image source (camera), while subsequent ones would be effectors (e.g. surgical tools, sensors). The robot will be based upon an existing prototype device. In addition to designing and building the platforms, specific aims include the creation of a feedback loop between newly developed, insertable sensor technology and effectors, with both surgeons and computers in the information-processing/control loop. The technology has two main components: hardware development of a novel, insertable, multi-degree of freedom sensor/effector platform, and software for control and a user interface for the surgeon. The initial part of the work will require development of these two components. The validation of the hardware/software/interface development will test all components of the imaging platform in a surgical mock-up environment. After confirming functionality, animal testing will compare the multiple degrees of freedom (measuring the ability of the device to provide images from different angles and quadrants of the abdominal cavity) and 3D image quality of the device with a standard laparoscope by measuring the outcomes of surgical techniques and procedures using each imaging system. Outcome parameters for these studies will include: time of each task, total time for each subject, complications caused by poor visualization, and subjective response of surgeon (was visualization with the imaging platform as good as, better than, or worse than a standard laparoscope?). The project includes sequential development of more advanced hardware and control software followed by animal trials after each development. The results will be statistically analyzed and validated to determine if there exist significant differences between current technology and the proposed device. The new technology has the potential to significantly improve health care in the following ways: increase the availability of minimal access surgery by shortening the learning curve; further reduce the invasiveness, and increase the safety, precision, and reproducibility of minimal access surgery; and reduce the cost of minimal access surgery.

描述（由申请人提供）：我们建议设计和构建小型、移动的、多功能平台，可放置在体腔内，以承担与微创手术相关的一些任务。出于目前腹腔镜成像设备的局限性，我们提出了一个团队的临床微创外科医生和机器人研究人员将开发和测试初始的微型机器人，其中包括图像源（相机），而随后的将效应器（例如手术工具，传感器）。该机器人将基于现有的原型设备。除了设计和构建平台外，具体目标还包括在新开发的可插入传感器技术和效应器之间创建反馈回路，其中外科医生和计算机都处于信息处理/控制回路中。该技术有两个主要组成部分：一种新型的、可插入的、多自由度传感器/效应器平台的硬件开发，以及用于控制的软件和外科医生的用户界面。这项工作的最初部分将需要开发这两个组成部分。硬件/软件/接口开发的确认将在手术模拟环境中测试成像平台的所有组件。在确认功能性后，动物试验将通过测量使用每种成像系统的手术技术和程序的结局，比较器械与标准腹腔镜的多个自由度（测量器械从腹腔的不同角度和象限提供图像的能力）和3D图像质量。这些研究的结局参数将包括：每项任务的时间、每例受试者的总时间、可视化不良引起的并发症和外科医生的主观反应（成像平台的可视化与标准腹腔镜一样好、更好还是更差？）。该项目包括顺序开发更先进的硬件和控制软件，然后在每次开发后进行动物试验。将对结果进行统计分析和确认，以确定当前技术与申报器械之间是否存在显著差异。这项新技术有可能通过以下方式显着改善医疗保健：通过缩短学习曲线来增加微创手术的可用性;进一步降低微创手术的侵入性，提高微创手术的安全性，精确性和可重复性;降低微创手术的成本。