Developing a clinically useful measure of dynamic pinch

开发一种临床上有用的动态夹捏测量方法

• 批准号: 6968849
• 负责人: Francisco J Valero-Cuevas
• 金额: $ 20.41万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-15 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6968849
• 关键词: biomechanics; clinical research; diagnosis design /evaluation; diagnostic tests; fingers; functional ability; human subject; limb movement; muscle strength; musculoskeletal disorder diagnosis; neuromuscular function; osteoarthritis; satisfaction

DESCRIPTION (provided by applicant): GOAL: To provide a much-needed simple, valid, and reliable measure of dynamic thumb forces that quantifies functional performance, impairment and recovery related to orthopedic and neurological diseases. The absence of an objective and sensitive outcome measure of dynamic thumb forces precludes informative clinical studies to optimize the choice, timing and options of treatment for each patient. APPROACH: We have designed a novel test to quantify the ability to produce dynamic thumb forces. The strength-dexterity (S-D) test is based on the principle of buckling of slender springs, and its current prototype consists of asking a person to attempt to compress each of 87 compression springs with different combinations of strength (stiffness) and dexterity (propensity to buckling) requirements. Our past clinical work has shown that the S-D Test is repeatable and is informative of the neuro-musculo-skeletal integrity of thumb with carpometacarpal osteoarthritis (CMC OA) better than measurements of pinch strength. We propose to refine the S-D Test into a clinically useful measure of dynamic thumb forces. AIM 1: Minimize burden to patient and clinician. We will shorten the S-D Test from 87 spring compressions to compressing at most 2 springs, 3 times each. Digital signal processing of fingertip kinematics and sensors embedded in this spring will fully characterize dynamic neuro-musculo-skeletal thumb function at each strength level via 3 continuous parameters. AIM 2: Validate the shortened S-D Test against established measures of hand function. We will deploy the S-D Test at the Hospital for Special Surgery to test the following hypotheses. PRIMARY HYPOTHESIS: The S-D Test correlates with available measures of hand function. SECONDARY HYPOTHESIS: The S-D Test correlates with patient satisfaction after treatment for CMC OA better than available measures of hand function. IMPACT: We seek to develop an assessment tool that is both simple and expeditious to administer, and can divulge a more comprehensive/reliable and quantifiable measure of this crucial thumb function. Developing the S-D Test into a quick, objective, and clinically valid measure of dynamic thumb forces will be instrumental to quantifying impairment and assessing effectiveness of treatments in today's clinical environment.

描述（由申请人提供）： 目标：提供急需的简单、有效且可靠的动态拇指力测量方法，以量化与骨科和神经系统疾病相关的功能表现、损伤和恢复。由于缺乏动态拇指力的客观和敏感的结果测量，无法进行信息丰富的临床研究来优化每个患者的治疗选择、时机和选择。 方法：我们设计了一种新颖的测试来量化产生动态拇指力的能力。强度-灵巧度 (S-D) 测试基于细长弹簧的屈曲原理，目前的原型包括要求一个人尝试压缩 87 个具有不同强度（刚度）和灵巧度（屈曲倾向）要求组合的压缩弹簧。我们过去的临床工作表明，S-D 测试是可重复的，并且比捏力测量更能提供患有腕掌骨关节炎 (CMC OA) 的拇指神经肌肉骨骼完整性的信息。我们建议将 S-D 测试改进为临床上有用的动态拇指力测量方法。 目标 1：最大限度地减少患者和临床医生的负担。我们将 S-D 测试从 87 次弹簧压缩缩短为最多压缩 2 个弹簧，每个弹簧压缩 3 次。该弹簧中嵌入的指尖运动学和传感器的数字信号处理将通过 3 个连续参数来全面表征每个强度级别的动态神经肌肉骨骼拇指功能。目标 2：根据既定的手部功能测量来验证缩短的 S-D 测试。我们将在特殊外科医院部署 S-D 测试来测试以下假设。主要假设：S-D 测试与现有的手部功能测量相关。第二个假设：S-D 测试与 CMC OA 治疗后患者满意度的相关性优于现有的手功能测量。 影响：我们寻求开发一种管理起来既简单又快捷的评估工具，并且可以对这一关键的拇指功能进行更全面/可靠和可量化的测量。将 S-D 测试开发为快速、客观且临床有效的动态拇指力测量方法，将有助于量化损伤和评估当今临床环境中治疗的有效性。