Training in Synaptic Neurobiology
突触神经生物学培训
基本信息
- 批准号:6919974
- 负责人:
- 金额:$ 25.81万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2002
- 资助国家:美国
- 起止时间:2002-07-01 至 2007-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (provided by applicant)
Integrated investigations using methods from biochemistry, molecular biology,
cell biology, anatomy and physiology are central to advancing our understanding
of synapse formation, organization and function. The purpose of the proposed
program is to provide postdoctoral and predoctoral training focused in synaptic
neurobiology. Our strategy for training gains from its ability to emphasize a
specific set of current issues that require an interdisciplinary approach while
still maintaining a breadth of training experience and exposure to a wide
variety of intellectual tools. This research is the foundation for
understanding - and hopefully alleviating - numerous neurological diseases. The
training will be provided by 7 faculty members of the Molecular, Cellular and
Integrative Neuroscience (MCIN) Program. The faculty members come from four
departments in two colleges. These faculty, along with 14 others, have
organized and teach a core neurobiology curriculum offering lecture,
literature, laboratory and discussion courses. Within the program are
individuals who can apply this fundamental knowledge in actual treatment of
neurological disorders, through their joint appointments as clinical scientists
at the Colorado State University Veterinary Teaching Hospital. In 2000 - 2001,
15 predoctoral and 20 postdoctoral students received training in the
laboratories of the training faculty. These trainees were supported from
individual research grants, postdoctoral and graduate fellowships, and by
graduate assistantships from the MCIN Program. Most of the predoctoral trainees
have degrees in traditional disciplines and were recruited either through
participating departments or through the MCIN program. All of the postdoctoral
trainees initiated contact with their mentors directly and were not recruited.
The program described in this proposal would allow us to recruit 4 postdoctoral
trainees and support 2 predoctoral students to participate in
cross-disciplinary projects involving more than one laboratory for up to 3
years. These recruits will be important for strengthening the interactions
between laboratories and will provide the trainees with a unique opportunity to
acquire the multidisciplinary skills needed for success in today's research
environment. All trainees will have access to modern cell and molecular
biological facilities including computer enhanced light, confocal and electron
microscopy (intermediate voltage), combined electrophysiology and
light/fluorescence microscopy equipment, macromolecular synthesis and
sequencing facilities, gene cloning and cell transfection laboratories, and a
high quality lab animal resource facility.
描述(由申请人提供)
利用生物化学,分子生物学,
细胞生物学、解剖学和生理学是推进我们理解
突触的形成、组织和功能。建议的目的
该计划旨在提供以突触为重点的博士后和博士前培训
神经生物学我们的培训战略得益于其强调
需要采取跨学科办法的一系列具体的当前问题,
仍然保持广泛的培训经验和接触广泛的
各种智力工具。这项研究是基础,
了解--并有望减轻--许多神经系统疾病。的
培训将由分子,细胞和
整合神经科学(MCIN)计划。教师来自四个
两个学院的部门。这些教师,沿着与其他14人,有
组织并教授核心神经生物学课程,
文学、实验和讨论课程。在该方案中,
个人谁可以应用这些基本知识在实际治疗
神经系统疾病,通过他们作为临床科学家的联合任命
在科罗拉多州立大学兽医教学医院。2000 - 2001年,
15名博士前和20名博士后学生接受了培训
培训学院的实验室。这些学员得到了来自
个人研究赠款、博士后和研究生奖学金,以及
MCIN项目的研究生助学金。大部分的博士前实习生
拥有传统学科的学位,
参与部门或通过MCIN计划。所有的博士后
受训人员直接与导师联系,没有被聘用。
该计划中所描述的这一建议将允许我们招募4博士后
培训生和支持2名博士生参加
涉及超过一个实验室的跨学科项目,
年这些新成员对于加强
实验室之间,并将为学员提供一个独特的机会,
获得在今天的研究成功所需的多学科技能
环境所有受训者都能接触到现代细胞和分子
生物设施,包括计算机增强光,共聚焦和电子
显微镜检查(中压),结合电生理学和
光学/荧光显微镜设备,大分子合成和
测序设施、基因克隆和细胞转染实验室,以及
高质量实验动物资源设施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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JAMES R BAMBURG其他文献
JAMES R BAMBURG的其他文献
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{{ truncateString('JAMES R BAMBURG', 18)}}的其他基金
Role of cofilin pathology in mouse models of cognitive impairment
丝切蛋白病理学在小鼠认知障碍模型中的作用
- 批准号:
8664331 - 财政年份:2013
- 资助金额:
$ 25.81万 - 项目类别:
Role of cofilin pathology in mouse models of cognitive impairment
丝切蛋白病理学在小鼠认知障碍模型中的作用
- 批准号:
8486049 - 财政年份:2013
- 资助金额:
$ 25.81万 - 项目类别:
ISOLATION AND CHARACTERIZATION OF CYTOPLASMIC COFILIN-ACTIN RODS
细胞质肌丝蛋白丝动蛋白-肌动蛋白棒的分离和表征
- 批准号:
8171304 - 财政年份:2010
- 资助金额:
$ 25.81万 - 项目类别:
ADF-Actin Rods in Neurodegenerative Diseases
ADF-肌动蛋白棒在神经退行性疾病中的作用
- 批准号:
6617076 - 财政年份:2001
- 资助金额:
$ 25.81万 - 项目类别:
ADF-Actin Rods in Neurodegenerative Diseases
ADF-肌动蛋白棒在神经退行性疾病中的作用
- 批准号:
6685913 - 财政年份:2001
- 资助金额:
$ 25.81万 - 项目类别:
ADF-Actin Rods in Neurodegenerative Diseases
ADF-肌动蛋白棒在神经退行性疾病中的作用
- 批准号:
6826802 - 财政年份:2001
- 资助金额:
$ 25.81万 - 项目类别:
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