Impulsivity Related to Cocaine Dependence & Trauma

与可卡因依赖相关的冲动

• 批准号: 6984578
• 负责人: ANGELA E. WALDROP
• 金额: $ 13.37万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6984578
• 关键词: behavioral /social science research tag; clinical research; cocaine; comorbidity; female; high risk behavior /lifestyle; impulsive behavior; patient oriented research; sex abuse; sex behavior; substance abuse related behavior; trauma

DESCRIPTION (provided by applicant): Training and research plans outlined in this proposal are meant to prepare the candidate to begin an independent research career in which she will design and conduct research on substance use, PTSD, and risky behaviors, with an emphasis on their relationship to impulsivity. The major training goals of the candidate are (a) develop expertise in SUD's: assessment, treatment, and research, (b) develop expertise in comorbidity of SUD's and PTSD, (c) develop expertise in human laboratory research and behavioral measurement of impulsivity, (d) gain expertise in behavioral HIV risk research, (e) enhance skills in grant writing and management, and (f) increase expertise in advanced statistical analyses. The specific aims of the research plan are to (a) investigate impulsivity among women with and without cocaine dependence and with and without at least subthreshold PTSD related to sexual trauma, and (b) to examine the relationships among HIV risk behaviors and the laboratory and self-report measures of impulsivity. The findings of the proposed study will then be used to inform future research in the area of impulsivity among women with comorbid substance use disorders and PTSD, perhaps leading eventually to the development of an intervention to address the harmful consequences of a variety of impulsive behaviors. The candidate has chosen three outstanding co-sponsors and one consultant to assist her in the development of the skills necessary to achieve the training goals and complete the proposed research plan. Dr. Kathleen Brady, the primary mentor, has a substantial record of research on substance use disorders and PTSD. Dr. Heidi Resnick has significant expertise in trauma-related research, particularly in sexual assault populations. Dr. Warren Bickel has published extensively in the area of impulsivity research with substance using populations. All three mentors are highly regarded for their work in their respective fields of research. Each has an extensive record of federal funding and mentoring junior colleagues. The research environment in Clinical Neuroscience at MUSC is an ideal environment for the candidate to meet her goals with a long history of successful grant funding, participant recruitment, and advanced research training.

描述（由申请人提供）： 该提案中概述的培训和研究计划旨在使候选人开始独立研究职业，在该职业中，她将对使用物质，PTSD和风险行为进行研究和进行研究，并着重于他们与冲动的关系。候选人的主要培训目标是（a）在SUD的：评估，治疗和研究方面发展专业知识，（b）在SUD和PTSD合并症方面发展专业知识，（c）（c）在人类实验室研究和冲动性的行为测量方面发展专业知识，（D）在行为HIV风险研究方面的提高技能，（e）提高了培养和管理方面的技能。研究计划的具体目的是（a）研究有或没有可卡因依赖性的女性以及与性创伤相关的有或没有下阈值的PTSD的冲动性，以及（b）检查HIV风险行为与实验室和自我报告的冲动措施之间的关系。然后，拟议的研究的发现将用于告知与合并药物使用障碍和PTSD妇女冲动领域的未来研究，也许最终导致了一种干预措施，以解决各种冲动行为的有害后果。 候选人选择了三位出色的共同发起人和一名顾问，以帮助她发展实现培训目标并完成拟议的研究计划所需的技能。主要导师凯瑟琳·布雷迪（Kathleen Brady）博士对药物使用障碍和PTSD的研究有了丰富的研究记录。海蒂·雷斯尼克（Heidi Resnick）博士在与创伤有关的研究方面具有重要的专业知识，尤其是性侵犯人群。沃伦·比克尔（Warren Bickel）博士在冲动研究领域广泛发表了使用人群的物质。这三位导师在各自的研究领域都受到高度评价。每个人都有大量的联邦资金和指导初级同事的记录。 MUSC临床神经科学的研究环境是候选人以悠久的赠款资金，参与者招聘和高级研究培训实现她目标的理想环境。