FASEB Conference: Skeletal muscle satellite/stem cells

描述（由申请人提供）：本申请寻求对即将于2005年6月11日至16日在亚利桑那州图森市举行的美国实验生物学学会联合会（FASEB）会议的部分支持，该会议题为“骨骼肌卫星和干细胞”。本次会议的总体目标是强调有关肌源性干细胞和祖细胞群体（如卫星细胞）的调节机制及其在发育，再生，衰老和肌病状态中的作用的最新进展。这将是该领域的第四次会议，从第一次到第三次会议的参与人数增加表明有必要专门讨论卫星和干细胞问题。从前三次会议的成功中可以清楚地看出，这个主题具有很高的兴趣，这次会议是唯一一次直接讨论肌肉卫星和干细胞群体的会议。该论坛将重点关注成人骨骼肌中的祖细胞/干细胞群的识别，特别关注其参与发育，肥大，再生，衰老和疾病。讨论将针对基于细胞的疗法的平台。 本次会议的会议包括：卫星细胞与发育、卫星细胞多样性、卫星细胞周期控制和信号传导、干细胞生物学和治疗策略、卫星细胞生长/ECM/生物工程、成人肌源性干细胞、骨骼肌肥大和再生、衰老、肌肉疾病和干细胞治疗研讨会。重要的是，本次会议的与会者将代表跨学科小组，将提供该领域最新发现的全面分析和整合。会议将进一步促进合作互动，以促进未来的进步和转化举措，旨在治疗和治愈肌病患者。

DESCRIPTION (provided by applicant): This application seeks partial support for the upcoming Federation of American Societies of Experimental Biology (FASEB) conference entitled, Skeletal muscle satellite and stem cells that will be held on June 11- 16, 2005 in Tucson, AZ. The overall objective of this meeting is to highlight recent advances pertaining to the regulatory mechanisms of myogenic stem cell and progenitor cell populations (such as satellite cells) and their role in development, regeneration, aging and myopathic states. This will be the fourth conference for this field and the increased participation from the first to the third meeting demonstrates the need for a conference dedicated to satellite and stem cells. It is clear from the successes of the previous three meetings that this topic is of high interest and this meeting represents the only conference that directly addresses muscle satellite and stem cell populations. This forum will focus on the identification of the progenitor/stem cell populations that are resident in adult skeletal muscle with a particular focus on their participation in development, hypertrophy, regeneration, aging and disease. Discussion will be directed toward platforms for cell based therapies. The sessions of this conference include: satellite cells and development, satellite cell diversity, satellite cell cycle control and signaling, stem cell biology and therapeutic strategies, satellite cell growth/ECM/ Bioengineering, myogenic stem cells in adults, skeletal muscle hypertrophy and regeneration, aging, muscle diseases and a stem cell therapy workshop. Importantly, the participants of this conference will represent interdisciplinary groups that will provide a comprehensive analysis and integration of recent discoveries for the field. The conference will further promote collaborative interactions in an attempt to promote future advancements and translational initiatives directed toward the treatment and cure of patients with myopathic diseases.