Principles of STD and HIV Research

描述(由申请者提供)：性病和艾滋病毒研究原理年度课程于1993年首次举办，主要介绍在性病/艾滋病毒领域从事研究工作所需的技能。自那时以来，已有600多名受训人员参加了培训，其中许多是妇女或少数族裔。跨学科的性传播疾病/艾滋病毒研究在设计研究和获得资金方面已变得至关重要。熟悉自己学科以外的研究视角为年轻调查人员提供了继续进行跨学科学习和协作的工具，并保持了广泛的调查可能性。本课程为行为学、临床、流行病学、统计学和病因学研究的入门培训提供了一个独特的机会，通过提供对这些广泛学科共同的语言和技能的实用概述。课程持续时间限制为两周，以鼓励正在建立积极研究职业生涯的个人，并允许居住在当地以外的人参加。课程目标是：1)向年轻研究人员介绍性病/艾滋病毒领域的关键研究领域和问题；2)使研究人员接触进行科学和符合伦理道德的研究所需的研究技术和工具，包括研究设计、实验方法、数据收集工具的开发、人体受试者的考虑和数据分析；3)向受训者介绍与性病/艾滋病毒研究有关的不同学科的基础知识，以促进研究合作；以及4)讨论成功竞争研究资金和出版自己的工作的策略。这门课程包括六个方面：1)性传播疾病/艾滋病毒跨学科研究的要点；2)感染的临床和流行病学方面；3)特定感染的发病机制；4)行为研究的方法论；5)成功和伦理研究的战略；6)生物统计分析的关键主题。课程记录以两卷的参考资料夹分发，其中包括演讲者的幻灯片和主要参考资料。在过去的几年里，该课程主要得到了NIH性病合作研究中心(CRC)的资金和教师支持。自1998年以来，每个社区合作中心每年都以资助教职员工或学生的旅费的形式提供捐助。由于性传播感染和局部杀微生物剂合作研究中心(STI TM CRCs)目前正在接受竞争性更新，2004年课程的资金将无法通过该机制获得。为此，目前的提案寻求通过R13机制获得等值资金。

DESCRIPTION (provided by applicant): The Annual Course on Principles of STD and HIV Research was first held in 1993 to provide an intensive overview of skills needed to pursue a research career in the field of STD/HIV. Since then, over 600 trainees, many of whom were women or racial/ethnic minorities, have attended. The importance of cross-disciplinary STD/HIV research has become essential in designing studies and in obtaining funding. Establishing familiarity with research perspectives outside one's own discipline provides young investigators with tools for continued interdisciplinary learning and collaboration, and for maintaining a broad scope of investigative possibilities. This course offers a unique opportunity for introductory training in behavioral, clinical, epidemiologic, statistical and pathogenesis research by providing a practically oriented overview of language and skills common to these broad disciplines. Course duration is limited to two weeks to encourage individuals who are establishing active research careers and allow those who reside outside of the local area to attend. Course objectives are to: 1) Introduce young investigators to critical research areas and questions in the field of STD/HIV; 2) Expose investigators to research techniques and tools needed to conduct scientifically and ethically sound studies, including study design, experimental approach, development of instruments for data collection, human subjects considerations, and data analysis; 3) Introduce trainees to fundamentals of different disciplines involved in STD/HIV research in order to foster research collaborations; and 4) Discuss strategies for successfully competing for research funds and publishing one's work. The course integrates six tracks: 1) Essentials of STD/HIV interdisciplinary research; 2) Clinical and epidemiologic aspects of infections; 3) Pathogenesis of specific infections; 4) Methodology of behavioral research; 5) Strategies for successful and ethical research; and 6) Critical topics in biostatistical analysis. The course proceedings are disseminated in a two-volume reference binder containing speakers' slides and key references. In past years, the course derived financial and faculty support primarily from the NIH STD Cooperative Research Centers (CRC). Since 1998, the CRCs have each annually contributed in the form of travel support for faculty or students. Because the STD CRCs, now designated the Sexually Transmitted Infections and Topical Microbicides Cooperative Research Centers (STI TM CRCs), are currently up for competitive renewal, funding for the 2004 course will not be available through that mechanism. For this reason, the current proposal seeks to obtain equivalent funding through the R13 mechanism.