AGITG TOP GEAR: A randomised phase II/III trial of preoperative chemoradiotherapy versus preoperative chemotherapy for resectable gastric cancer

虽然手术切除胃癌传统上被认为是治愈这种疾病的唯一方法，但最近在手术前后使用化疗和/或放射治疗取得了一些进展。对于最好的治疗方法和顺序，医生们的意见仍然存在分歧。这项试验将解决一个重要的问题，即在提高胃癌治愈率方面，联合化疗加放射治疗是否比单独化疗更有效。

While surgery to remove stomach cancer has been traditionally accepted as the only way to potentially cure the disease, there have been several recent advances using chemotherapy and/or radiotherapy both before and after surgery. Doctors' opinions remain divided regarding best treatments to give and in what order. This trial will address the important question of whether combined chemotherapy plus radiotherapy is more effective than chemotherapy alone in improving cure rates for stomach cancer.