THE BIOLOGY OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISEASES

描述(由申请人提供)：南卡罗来纳医科大学神经科学系和精神病学和行为科学系的成员建议开发一门研究生水平的神经学和神经精神病学疾病生物学课程。总体目标是(1)让研究生积极学习神经系统疾病潜在的神经生物学基础，(2)将教学材料作为基于网络的课程向广大神经科学界传播。这门4学分的课程将是神经科学博士课程的必修课，也将向整个神经科学界开放。它将安排在研究生二年级的春季学期。本课程将涵盖一系列神经学和神经精神病学疾病的潜在机制和病理生物学。每个2小时的会议将包括特定疾病的临床陈述、转化研究、药物开发/治疗以及与该疾病相关的临床研究中的伦理问题(1小时)，以及关于该疾病的神经生物学基础和动物模型的讨论(2小时)。在可能的情况下，将提供对患者的现场访谈或预先录制的访谈。临床和基础科学家将在课程中以团队形式教授每个主题，在外部专业知识可以增进理解的领域，该领域的知名神经科学家将被邀请讲课，并与学生共度大量时间。课程材料将在神经科学系研究生学习网页上分发。

DESCRIPTION (provided by applicant): Members of the Department of Neurosciences and the Department of Psychiatry and Behavioral Sciences of the Medical University of South Carolina propose to develop a graduate-level course on the Biology of Neurological and Neuropsychiatric Diseases. The overall goals are to (1) involve graduate students in active learning about the neurobiological substrates underlying disorders of the nervous system and to (2) disseminate the instructional material as a web-based course to the neuroscience community at large. This 4 credit course will be a required part of the Ph.D. program in Neurosciences and also will be open to the neuroscience community at large. It will be scheduled during the spring semester of the second year of graduate study. The course will cover the underlying mechanisms and pathobiology of a wide range of neurological and neuropsychiatric diseases. Each 2 hour session will include clinical presentations of a particular disorder, translational research, medications development/treatment, and ethical issues in clinical research relevant to the disorder (hour 1), and discussions of the neurobiological substrates and animal models of the disorder (hour 2). Where possible, live or pre-recorded interviews of patients will be presented. Clinical and basic scientists will teach each topic in the course as a team and, in areas where outside expertise would enhance understanding, prominent neuroscientists in the field will be invited to lecture and spend significant time with the students. Course materials will be disseminated on the Department of Neurosciences graduate studies webpage.