COCA: Pilot Core C
COCA:试点核心 C
基本信息
- 批准号:10630227
- 负责人:
- 金额:$ 16.93万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-15 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:AdvertisementsBehavioral MechanismsClinicalClinical InvestigatorClinical ResearchCocaine DependenceConsultationsDevelopmentDrug AddictionEnvironmentExtramural ActivitiesFacultyFosteringFundingGoalsGrantGrowthInfrastructureInvestigationMentorsMissionMonitorNeurosciencesOpiate AddictionOpioidPilot ProjectsPublicationsRelapseReportingResearchResearch PersonnelResearch Project GrantsScienceScientistSubstance Use DisorderSupervisionTalentsWorkaddictionclinical translationcocaine self-administrationmemberneuroadaptationneurobiological mechanismnew technologynext generationnovel therapeutic interventionpre-clinicalpre-clinical researchsynergism
项目摘要
PROJECT SUMMARY – Core C
Pilot Core C will oversee the execution and development of pilot projects that bring new
technologies and new investigators into the Center for Cocaine and Opioid Addiction (COCA).
MUSC neuroscience has undergone dramatic growth within the last 5 years that has expanded
the pool of young, talented investigators in preclinical and clincal arenas. The Pilot Core will
provide an opportunity to mentor some of these young investigators into the field of addiction
under the supervision of senior COCA investigators. Both preclinical and clinical pilot projects
will be solicited by advertisement and competitvely reviewed by the COCA Internal Advisory
Board. Once funded, the progress of projects will undergo extensive monitoring by the Core C
Directors and the Internal Advisory Board (IAB). The proposed pilot grants will be evaluated and
prioritized to promote early stage or early established investigators whose work synergizes with
the overall COCA mission. Each pilot awardee will work closely with a senior mentor and report
their progress regularly to the IAB. To illustrate the potential of the Pilot Core to assist in the
development of young investigators and to promote cutting edge preclinical and clinical
research, the proposal outlines four possible pilot projects that, if formally submitted in a call for
pilot grants, will be considered in a competitive manner if the COCA is funded.
项目摘要-核心C
试点核心C将监督试点项目的执行和发展,
技术和新的研究人员进入可卡因和阿片类药物成瘾中心(COCA)。
MUSC神经科学在过去5年中经历了戏剧性的增长,
临床前和临床领域的年轻、有才华的研究人员。Pilot Core将
提供了一个机会,指导这些年轻的调查人员进入成瘾领域,
在COCA高级调查员的监督下临床前和临床试验项目
将通过广告征集,并由COCA内部顾问进行竞争性审查
纸板.一旦获得资助,项目的进展将受到核心C的广泛监督
董事和内部咨询委员会(IAB)。将对拟议的试点赠款进行评估,
优先促进早期阶段或早期建立的调查员,他们的工作与
整个COCA使命。每个试点获奖者将与高级导师密切合作,并报告
他们的进展定期向IAB报告。为了说明试点核心在协助
培养年轻的研究人员,促进尖端的临床前和临床
该提案概述了四个可能的试点项目,如果正式提交,
如果COCA得到资助,将以竞争的方式考虑试点赠款。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Jacqueline F. McGinty其他文献
Oxytocin decreases methamphetamine-seeking and gene expression changes in rats after traumatic stress
- DOI:
10.1016/j.drugalcdep.2016.08.382 - 发表时间:
2017-02-01 - 期刊:
- 影响因子:
- 作者:
Jacqueline F. McGinty - 通讯作者:
Jacqueline F. McGinty
Seizure-Induced Alterations of Opioid Peptide and Zinc Metabolism in the Hippocampus of Rats
癫痫发作引起的大鼠海马阿片肽和锌代谢的改变
- DOI:
10.1016/b978-0-12-506455-2.50027-7 - 发表时间:
1988 - 期刊:
- 影响因子:6.1
- 作者:
Jacqueline F. McGinty;Tomoyuki Kanamatsu;Jau;JOHN D. Morton;Christopher J. Frederickson - 通讯作者:
Christopher J. Frederickson
Will the promise of translational neuropsychopharmacology research ever deliver? The lion’s roar; the kitten’s purr
转化神经精神药理学研究的前景能否实现?
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
Jacqueline F. McGinty;Victoria Arango;Kathleen T. Brady;Sandra D. Comer;Rita Z. Goldstein;E. Nestler;William W. Stoops;Michael A. Nader - 通讯作者:
Michael A. Nader
Erratum to: Short and long access to cocaine self-administration activates tyrosine phosphatase STEP and attenuates GluN expression but differentially regulates GluA expression in the prefrontal cortex
- DOI:
10.1007/s00213-013-3155-0 - 发表时间:
2013-06-05 - 期刊:
- 影响因子:3.300
- 作者:
Wei-Lun Sun;Agnieszka Zelek-Molik;Jacqueline F. McGinty - 通讯作者:
Jacqueline F. McGinty
Lennart Heimer: in memoriam (1930–2007)
- DOI:
10.1007/s00429-008-0194-0 - 发表时间:
2008-08-08 - 期刊:
- 影响因子:2.900
- 作者:
Suzanne N. Haber;Jacqueline F. McGinty;Enrico Mugnaini;Laszlo Zaborszky - 通讯作者:
Laszlo Zaborszky
Jacqueline F. McGinty的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Jacqueline F. McGinty', 18)}}的其他基金
Pathway-specific Intervention in Prelimbic Cortical Circuitry Decreases Cocaine-seeking
对前额皮质回路进行特定通路干预可减少可卡因寻求
- 批准号:
10674953 - 财政年份:2020
- 资助金额:
$ 16.93万 - 项目类别:
Pathway-specific Intervention in Prelimbic Cortical Circuitry Decreases Cocaine-seeking
对前额皮质回路进行特定通路干预可减少可卡因寻求
- 批准号:
10268963 - 财政年份:2020
- 资助金额:
$ 16.93万 - 项目类别:
Pathway-specific Intervention in Prelimbic Cortical Circuitry Decreases Cocaine-seeking
对前额皮质回路进行特定通路干预可减少可卡因寻求
- 批准号:
10453594 - 财政年份:2020
- 资助金额:
$ 16.93万 - 项目类别:
COCA - Project 2 Preventing Drug-induced Neuroadaptations in Prelimbic Cortex
COCA - 项目 2 预防前边缘皮层药物诱导的神经适应
- 批准号:
10630231 - 财政年份:2019
- 资助金额:
$ 16.93万 - 项目类别:
COCA - Project 2 Preventing Drug-induced Neuroadaptations in Prelimbic Cortex
COCA - 项目 2 预防前边缘皮层药物诱导的神经适应
- 批准号:
10404585 - 财政年份:2019
- 资助金额:
$ 16.93万 - 项目类别:
Prevention of Cocaine-induced Prefrontal ERK Shutoff During Early Withdrawal
早期戒断期间预防可卡因引起的前额叶 ERK 关闭
- 批准号:
8787464 - 财政年份:2013
- 资助金额:
$ 16.93万 - 项目类别:
Prevention of Cocaine-induced Prefrontal ERK Shutoff During Early Withdrawal
早期戒断期间预防可卡因引起的前额叶 ERK 关闭
- 批准号:
9187444 - 财政年份:2013
- 资助金额:
$ 16.93万 - 项目类别:
Prevention of Cocaine-induced Prefrontal ERK Shutoff During Early Withdrawal
早期戒断期间预防可卡因引起的前额叶 ERK 关闭
- 批准号:
8439031 - 财政年份:2013
- 资助金额:
$ 16.93万 - 项目类别:
相似海外基金
CAREER: Computing rules of the social brain: behavioral mechanisms of function and dysfunction in biological collectives
职业:社会大脑的计算规则:生物集体中功能和功能障碍的行为机制
- 批准号:
2338596 - 财政年份:2024
- 资助金额:
$ 16.93万 - 项目类别:
Continuing Grant
Investigating Behavioral Mechanisms and Efficacy of a Provider-Directed Intervention for HPV Vaccine Promotion in Real-World Dental Settings
研究现实世界牙科环境中 HPV 疫苗推广的行为机制和提供者导向干预措施的效果
- 批准号:
10893076 - 财政年份:2023
- 资助金额:
$ 16.93万 - 项目类别:
Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults with Depression (ENSURE)
情绪认知:在患有抑郁症的老年人中建立结构和神经行为机制(ENSURE)
- 批准号:
10667191 - 财政年份:2023
- 资助金额:
$ 16.93万 - 项目类别:
Neural and Behavioral Mechanisms of Angry Hostility in Depression
抑郁症中愤怒敌意的神经和行为机制
- 批准号:
10744840 - 财政年份:2023
- 资助金额:
$ 16.93万 - 项目类别:
Investigating Behavioral Mechanisms and Efficacy of a Provider-Directed Intervention for HPV Vaccine Promotion in Real-World Dental Settings
研究现实世界牙科环境中 HPV 疫苗推广的行为机制和提供者导向干预措施的效果
- 批准号:
10586610 - 财政年份:2023
- 资助金额:
$ 16.93万 - 项目类别:
Neural and behavioral mechanisms of song learning in zebra finches
斑胸草雀鸣叫学习的神经和行为机制
- 批准号:
10678601 - 财政年份:2023
- 资助金额:
$ 16.93万 - 项目类别:
Mobile Technology to Identify Behavioral Mechanisms Linking Genetic Variation and Depression
移动技术识别遗传变异和抑郁症之间的行为机制
- 批准号:
10728697 - 财政年份:2023
- 资助金额:
$ 16.93万 - 项目类别:
Diversity Supplement to Beta-Adrenergic Modulation of Drug Cue Reactivity: Neural and Behavioral Mechanisms
药物提示反应性β-肾上腺素能调节的多样性补充:神经和行为机制
- 批准号:
10838177 - 财政年份:2022
- 资助金额:
$ 16.93万 - 项目类别:
Beta-Adrenergic Modulation of Drug Cue Reactivity: Neural and Behavioral Mechanisms
药物提示反应性的β-肾上腺素调节:神经和行为机制
- 批准号:
10446411 - 财政年份:2022
- 资助金额:
$ 16.93万 - 项目类别:
Beta-Adrenergic Modulation of Drug Cue Reactivity: Neural and Behavioral Mechanisms
药物提示反应性的β-肾上腺素调节:神经和行为机制
- 批准号:
10618895 - 财政年份:2022
- 资助金额:
$ 16.93万 - 项目类别: