Understanding the mechanisms leading to age-related hearing loss

老年性听力损失(ARHL)是老年人最常见的感觉障碍，是导致听力敏感性进行性丧失的主要原因。到2030年，英国约有1450万人(全球5亿人)将受到ARHL的影响。急性淋巴细胞性白血病还与社会孤立、抑郁和神经退行性疾病风险增加有关。阻碍ARHL新疗法发展的主要障碍是缺乏对为什么我们随着年龄的增长而逐渐丧失听力的理解。

Age-related hearing loss (ARHL), which causes the progressive loss of hearing sensitivity, is the most common sensory deficit in elderly. Approximately 14.5M people in the UK (500M worldwide) will be affected by ARHL by 2030. ARHL is also associated with social isolation, depression and an increased risk for neurodegenerative diseases. The major obstacle preventing the development of new treatments for ARHL is a lack of understanding about why we progressively lose hearing with age.