Understanding the mechanisms leading to age-related hearing loss

了解导致与年龄相关的听力损失的机制

• 批准号: 2594280
• 金额: --
• 依托单位: University of Sheffield
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2594280
• 关键词: Understanding; mechanisms; leading; age; related

Age-related hearing loss (ARHL), which causes the progressive loss of hearing sensitivity, is the most common sensory deficit in elderly. Approximately 14.5M people in the UK (500M worldwide) will be affected by ARHL by 2030. ARHL is also associated with social isolation, depression and an increased risk for neurodegenerative diseases. The major obstacle preventing the development of new treatments for ARHL is a lack of understanding about why we progressively lose hearing with age.

老年性听力损失（ARHL）是老年人最常见的感觉功能障碍，是一种进行性听力损失。到2030年，英国约有1450万人（全球5亿人）将受到ARHL的影响。ARHL还与社交孤立、抑郁和神经退行性疾病风险增加有关。阻碍ARHL新疗法开发的主要障碍是对为什么我们随着年龄的增长逐渐丧失听力缺乏了解。