UIC-JNMC Women's & Children's Research Unit

UIC-JNMC 女子

• 批准号: 7001056
• 负责人: RICHARD J DERMAN
• 金额: $ 6.17万
• 依托单位: UNIVERSITY OF MISSOURI KANSAS CITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-23 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7001056
• 关键词: India; cooperative study; culture; disease /disorder proneness /risk; female; health behavior; health science research analysis /evaluation; hemorrhage; hormone therapy; human morbidity; human mortality; human subject; human therapy evaluation; medical complication; outcomes research; patient oriented research; postpartum; prostaglandin E; prostaglandin analogs; public health; questionnaires; socioeconomics; women' s health

The Division of Women's Health (Department of Obstetrics and Gynecology) in conjunction with the Division of Neonatology (Department of Pediatrics), College of Medicine, University of Illinois at Chicago (IJIC) are applying for a Global Network for Women's and Children's Health Research Unit. Together with our international partner, Jawaharlal Nehru Medical College located in Belgaum, Karnataka, India, we propose: 1) to expand and strengthen the existing research infrastructure in India and to increase public health capabilities in the area of maternal and child health, 2) to build on the collaborative relationship existing between JN Medical College and UIC and to provide opportunities for collaborative research that focuses on leading causes of morbidity and mortality in pregnancy and early childhood. Consistent with an objective for establishing Global Network Research Units, we have a commitment to designing, implementing, and evaluating evidence-based interventions and supporting our international partner, JNMC, in carrying out basic biomedical and behavioral research, clinical and translational research, and associated evaluative research that will improve health status for mothers, young children, and families in India. Out initial collaborative effort will be to conduct a prospective study directed at the problem of postpartum hemorrhage. Our study will be carried out in the Belgaum District (State of Karnataka) and test the hypothesis that the administration of misoprostol to women after delivery can reduce postpartum hemorrhage and related adverse outcomes. Additionally, we will do a case comparison of women presenting to study sites with hemorrhage and subsequently dying and women who survive postpartum hemorrhage to determine if there are differences in the two groups.

妇女保健处（妇产科系）与芝加哥伊利诺斯大学医学院新生儿科（儿科系）正在申请设立一个全球妇幼保健网研究股。与我们的国际合作伙伴，位于印度卡纳塔克邦贝尔高姆的贾瓦哈拉尔·尼赫鲁医学院一起，我们建议：（1）扩大和加强印度现有的研究基础设施，提高妇幼保健领域的公共卫生能力;（二）建立在JN医学院和UIC之间现有的合作关系，并提供合作研究的机会，重点是领导怀孕和幼儿期发病和死亡的原因。与建立全球网络研究单位的目标相一致，我们致力于设计，实施和评估循证干预措施，并支持我们的国际合作伙伴JNMC开展基础生物医学和行为研究，临床和转化研究以及相关的评估研究，这将改善印度母亲，幼儿和家庭的健康状况。我们最初的合作努力将是针对产后出血问题进行一项前瞻性研究。我们的研究将在贝尔高姆区（卡纳塔克邦）进行，并检验对分娩后妇女给予米索前列醇可以减少产后出血和相关不良后果的假设。此外，我们将对因出血而到研究中心并随后死亡的妇女和产后出血幸存的妇女进行病例比较，以确定两组是否存在差异。